3e6p: Difference between revisions
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{{STRUCTURE_3e6p| PDB=3e6p | SCENE= }} | |||
===Crystal structure of human meizothrombin desF1=== | |||
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{{ABSTRACT_PUBMED_18854941}} | |||
==Disease== | |||
Known disease associated with this structure: Dysprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hyperprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hypoprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]] | |||
==About this Structure== | |||
3E6P is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E6P OCA]. | |||
==Reference== | |||
Na(+) binding to meizothrombin desF1., Papaconstantinou ME, Gandhi PS, Chen Z, Bah A, Di Cera E, Cell Mol Life Sci. 2008 Nov;65(22):3688-97. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18854941 18854941] | |||
New insights into the regulation of the blood clotting cascade derived from the X-ray crystal structure of bovine meizothrombin des F1 in complex with PPACK., Martin PD, Malkowski MG, Box J, Esmon CT, Edwards BF, Structure. 1997 Dec 15;5(12):1681-93. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9438869 9438869] | |||
[[Category: Homo sapiens]] | |||
[[Category: Thrombin]] | |||
[[Category: Bah, A.]] | |||
[[Category: Cera, E Di.]] | |||
[[Category: Chen, Z.]] | |||
[[Category: Gandhi, P.]] | |||
[[Category: Papaconstantinou, M E.]] | |||
[[Category: Acute phase]] | |||
[[Category: Allostery]] | |||
[[Category: Blood coagulation]] | |||
[[Category: Calcium]] | |||
[[Category: Cleavage on pair of basic residue]] | |||
[[Category: Disease mutation]] | |||
[[Category: Gamma-carboxyglutamic acid]] | |||
[[Category: Glycoprotein]] | |||
[[Category: Hydrolase]] | |||
[[Category: Kringle]] | |||
[[Category: Linkage]] | |||
[[Category: Meizothrombin]] | |||
[[Category: Na+ binding]] | |||
[[Category: Pharmaceutical]] | |||
[[Category: Polymorphism]] | |||
[[Category: Protease]] | |||
[[Category: Secreted]] | |||
[[Category: Serine protease]] | |||
[[Category: Thrombin]] | |||
[[Category: Zymogen]] | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Nov 20 07:45:00 2008'' | |||