3e6p: Difference between revisions

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'''Unreleased structure'''
{{Seed}}
[[Image:3e6p.jpg|left|200px]]


The entry 3e6p is ON HOLD until Nov 18 2009
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{{STRUCTURE_3e6p|  PDB=3e6p  |  SCENE=  }}


Authors: Papaconstantinou, M.E., Gandhi, P., Chen, Z., Bah, A., Di Cera, E.
===Crystal structure of human meizothrombin desF1===


Description: Crystal structure of human meizothrombin desF1


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 5 11:40:45 2008''
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{{ABSTRACT_PUBMED_18854941}}
 
==Disease==
Known disease associated with this structure: Dysprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hyperprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hypoprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]]
 
==About this Structure==
3E6P is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E6P OCA].
 
==Reference==
Na(+) binding to meizothrombin desF1., Papaconstantinou ME, Gandhi PS, Chen Z, Bah A, Di Cera E, Cell Mol Life Sci. 2008 Nov;65(22):3688-97. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18854941 18854941]
 
New insights into the regulation of the blood clotting cascade derived from the X-ray crystal structure of bovine meizothrombin des F1 in complex with PPACK., Martin PD, Malkowski MG, Box J, Esmon CT, Edwards BF, Structure. 1997 Dec 15;5(12):1681-93. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9438869 9438869]
[[Category: Homo sapiens]]
[[Category: Thrombin]]
[[Category: Bah, A.]]
[[Category: Cera, E Di.]]
[[Category: Chen, Z.]]
[[Category: Gandhi, P.]]
[[Category: Papaconstantinou, M E.]]
[[Category: Acute phase]]
[[Category: Allostery]]
[[Category: Blood coagulation]]
[[Category: Calcium]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Disease mutation]]
[[Category: Gamma-carboxyglutamic acid]]
[[Category: Glycoprotein]]
[[Category: Hydrolase]]
[[Category: Kringle]]
[[Category: Linkage]]
[[Category: Meizothrombin]]
[[Category: Na+ binding]]
[[Category: Pharmaceutical]]
[[Category: Polymorphism]]
[[Category: Protease]]
[[Category: Secreted]]
[[Category: Serine protease]]
[[Category: Thrombin]]
[[Category: Zymogen]]
 
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