3ela: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
3ELA is a | 3ELA is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ELA OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:18640965</ref><references group="xtra"/> | |||
[[Category: Coagulation factor VIIa]] | [[Category: Coagulation factor VIIa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Bjelke, J R.]] | [[Category: Bjelke, J R.]] | ||
[[Category: Fodje, M.]] | [[Category: Fodje, M.]] | ||
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[[Category: Zymogen]] | [[Category: Zymogen]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:17:26 2009'' | ||
Revision as of 10:17, 17 February 2009
Crystal structure of active site inhibited coagulation factor VIIA mutant in complex with soluble tissue factor
Template:ABSTRACT PUBMED 18640965
Disease
Known disease associated with this structure: Factor VII deficiency OMIM:[227500], Myocardial infarction, decreased susceptibility to OMIM:[227500]
About this Structure
3ELA is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Bjelke JR, Olsen OH, Fodje M, Svensson LA, Bang S, Bolt G, Kragelund BB, Persson E. Mechanism of the Ca2+-induced enhancement of the intrinsic factor VIIa activity. J Biol Chem. 2008 Sep 19;283(38):25863-70. Epub 2008 Jul 17. PMID:18640965 doi:10.1074/jbc.M800841200
Page seeded by OCA on Tue Feb 17 12:17:26 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Coagulation factor VIIa
- Homo sapiens
- Bjelke, J R.
- Fodje, M.
- Svensson, L A.
- Allosteric regulation
- Allostery
- Alternative splicing
- Blood clotting
- Blood coagulation
- Calcium
- Cleavage on pair of basic residue
- Disease mutation
- Egf-like domain
- Exosite
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydrolase
- Hydroxylation
- Lipoprotein
- Membrane
- Palmitate
- Pharmaceutical
- Polymorphism
- Protease
- Secreted
- Serine protease
- Transmembrane
- Zymogen