2w26: Difference between revisions

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{{Seed}}
{{Seed}}
[[Image:2w26.jpg|left|200px]]
[[Image:2w26.png|left|200px]]


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==Reference==
==Reference==
Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor., Roehrig S, Straub A, Pohlmann J, Lampe T, Pernerstorfer J, Schlemmer KH, Reinemer P, Perzborn E, J Med Chem. 2005 Sep 22;48(19):5900-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16161994 16161994]
<ref group="xtra">PMID:16161994</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Lampe, T.]]
[[Category: Lampe, T.]]
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[[Category: Zymogen]]
[[Category: Zymogen]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 12 10:43:44 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 17:41:33 2009''

Revision as of 15:41, 16 February 2009

File:2w26.png

Template:STRUCTURE 2w26

FACTOR XA IN COMPLEX WITH BAY59-7939

Template:ABSTRACT PUBMED 16161994

About this Structure

2W26 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Roehrig S, Straub A, Pohlmann J, Lampe T, Pernerstorfer J, Schlemmer KH, Reinemer P, Perzborn E. Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor. J Med Chem. 2005 Sep 22;48(19):5900-8. PMID:16161994 doi:10.1021/jm050101d

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