1u1s: Difference between revisions
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New page: left|200px<br /><applet load="1u1s" size="450" color="white" frame="true" align="right" spinBox="true" caption="1u1s, resolution 1.60Å" /> '''Hfq protein from Pse... |
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[[Image:1u1s.gif|left|200px]]<br /><applet load="1u1s" size=" | [[Image:1u1s.gif|left|200px]]<br /><applet load="1u1s" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="1u1s, resolution 1.60Å" /> | caption="1u1s, resolution 1.60Å" /> | ||
'''Hfq protein from Pseudomonas aeruginosa. Low-salt crystals'''<br /> | '''Hfq protein from Pseudomonas aeruginosa. Low-salt crystals'''<br /> | ||
==Overview== | ==Overview== | ||
The structure of the Hfq protein from Pseudomonas aeruginosa was | The structure of the Hfq protein from Pseudomonas aeruginosa was determined using two different ionic conditions. In both cases the molecules formed identical hexameric rings, but some variations in the crystal packing were revealed. Hfq belongs to the family of Sm/LSm proteins, the members of which can form hexameric as well as heptameric rings. Comparative analysis of known structures of this protein family shows that the fragment of the Sm-fold responsible for oligomerization is strongly structurally conserved. In the heptameric ring, three conserved hydrogen bonds between beta-strands of adjacent molecules hold together the monomers, whereas in the hexameric rings of Hfq an additional conserved inaccessible hydrogen bond between neighbouring monomers is observed. | ||
==About this Structure== | ==About this Structure== | ||
1U1S is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http:// | 1U1S is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U1S OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: Kachalova, G.]] | [[Category: Kachalova, G.]] | ||
[[Category: Moll, I.]] | [[Category: Moll, I.]] | ||
[[Category: Nikonov, S | [[Category: Nikonov, S V.]] | ||
[[Category: Nikulin, A | [[Category: Nikulin, A D.]] | ||
[[Category: Perederina, I.]] | [[Category: Perederina, I.]] | ||
[[Category: RSGI, RIKEN | [[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]] | ||
[[Category: Stolboushkina, E | [[Category: Stolboushkina, E A.]] | ||
[[Category: Vassilieva, I | [[Category: Vassilieva, I M.]] | ||
[[Category: Vassylyev, D.]] | [[Category: Vassylyev, D.]] | ||
[[Category: Yokoyama, S.]] | [[Category: Yokoyama, S.]] | ||
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[[Category: structural genomics]] | [[Category: structural genomics]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:19:53 2008'' | ||
