1gl7: Difference between revisions
New page: left|200px<br /> <applet load="1gl7" size="450" color="white" frame="true" align="right" spinBox="true" caption="1gl7, resolution 3.0Å" /> '''PLASMID COUPLING PRO... |
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==About this Structure== | ==About this Structure== | ||
1GL7 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]] with CL and ANP as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GL7 OCA]]. | 1GL7 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]] with CL and ANP as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Site: ANA. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GL7 OCA]]. | ||
==Reference== | ==Reference== | ||
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[[Category: type iv secretion system conjugative coupling protein from plasmid]] | [[Category: type iv secretion system conjugative coupling protein from plasmid]] | ||
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 13:53:02 2007'' | ||
Revision as of 11:48, 30 October 2007
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PLASMID COUPLING PROTEIN TRWB IN COMPLEX WITH THE NON-HYDROLISABLE ATP-ANALOGUE ADPNP.
Overview
The transfer of DNA across membranes and between cells is a central, biological process; however, its molecular mechanism remains unknown. In, prokaryotes, trans-membrane passage by bacterial conjugation, is the main, route for horizontal gene transfer. It is the means for rapid acquisition, of new genetic information, including antibiotic resistance by pathogens., Trans-kingdom gene transfer from bacteria to plants or fungi and even, bacterial sporulation are special cases of conjugation. An integral, membrane DNA-binding protein, called TrwB in the Escherichia coli R388, conjugative system, is essential for the conjugation process. This large, multimeric protein is responsible for recruiting the relaxosome, DNA-protein complex, and participates in the transfer of a single DNA, strand ... [(full description)]
About this Structure
1GL7 is a [Single protein] structure of sequence from [Escherichia coli] with CL and ANP as [ligands]. Structure known Active Site: ANA. Full crystallographic information is available from [OCA].
Reference
The bacterial conjugation protein TrwB resembles ring helicases and F1-ATPase., Gomis-Ruth FX, Moncalian G, Perez-Luque R, Gonzalez A, Cabezon E, de la Cruz F, Coll M, Nature. 2001 Feb 1;409(6820):637-41. PMID:11214325
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