3f66: Difference between revisions

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'''Unreleased structure'''
{{Seed}}
[[Image:3f66.jpg|left|200px]]


The entry 3f66 is ON HOLD
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{{STRUCTURE_3f66|  PDB=3f66 |  SCENE=  }}


Authors: Meier, C., Ceska, T.
===Human c-Met Kinase in complex with quinoxaline inhibitor===


Description: Human c-Met Kinase in complex with quinoxaline inhibitor


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 10 14:38:56 2008''
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{{ABSTRACT_PUBMED_19059779}}
 
==Disease==
Known disease associated with this structure: Hepatocellular carcinoma, childhood type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]], Renal cell carcinoma, papillary, familial and sporadic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]], Autism, suseptibility to, 9 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]]
 
==About this Structure==
3F66 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F66 OCA].
 
==Reference==
Discovery of a novel series of quinoxalines as inhibitors of c-Met kinase., Porter J, Lumb S, Lecomte F, Reuberson J, Foley A, Calmiano M, le Riche K, Edwards H, Delgado J, Franklin RJ, Gascon-Simorte JM, Maloney A, Meier C, Batchelor M, Bioorg Med Chem Lett. 2008 Nov 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/19059779 19059779]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Ceska, T.]]
[[Category: Meier, C.]]
[[Category: Alternative splicing]]
[[Category: Atp-binding]]
[[Category: C-met]]
[[Category: Chromosomal rearrangement]]
[[Category: Disease mutation]]
[[Category: Glycoprotein]]
[[Category: Kinase]]
[[Category: Membrane]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Protein kinase]]
[[Category: Proto-oncogene]]
[[Category: Quinoxaline]]
[[Category: Receptor]]
[[Category: Repeat]]
[[Category: Signal]]
[[Category: Transferase]]
[[Category: Transmembrane]]
[[Category: Tyrosine-protein kinase.]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 24 11:36:15 2008''

Revision as of 09:36, 24 December 2008

File:3f66.jpg

Template:STRUCTURE 3f66

Human c-Met Kinase in complex with quinoxaline inhibitor

Template:ABSTRACT PUBMED 19059779

Disease

Known disease associated with this structure: Hepatocellular carcinoma, childhood type OMIM:[164860], Renal cell carcinoma, papillary, familial and sporadic OMIM:[164860], Autism, suseptibility to, 9 OMIM:[164860]

About this Structure

3F66 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Discovery of a novel series of quinoxalines as inhibitors of c-Met kinase., Porter J, Lumb S, Lecomte F, Reuberson J, Foley A, Calmiano M, le Riche K, Edwards H, Delgado J, Franklin RJ, Gascon-Simorte JM, Maloney A, Meier C, Batchelor M, Bioorg Med Chem Lett. 2008 Nov 21. PMID:19059779

Page seeded by OCA on Wed Dec 24 11:36:15 2008

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