3emg: Difference between revisions

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{{Seed}}
[[Image:3emg.png|left|200px]]
[[Image:3emg.png|left|200px]]


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{{STRUCTURE_3emg|  PDB=3emg  |  SCENE=  }}  
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===Discovery and SAR of novel 4-thiazolyl-2-phenylaminopyrimidines as potent inhibitors of spleen tyrosine kinase (SYK)===
===Discovery and SAR of novel 4-thiazolyl-2-phenylaminopyrimidines as potent inhibitors of spleen tyrosine kinase (SYK)===


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{{ABSTRACT_PUBMED_18938080}}
{{ABSTRACT_PUBMED_18938080}}


==About this Structure==
==About this Structure==
3EMG is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EMG OCA].  
[[3emg]] is a 1 chain structure of [[Tyrosine kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EMG OCA].  
 
==See Also==
*[[Tyrosine kinase|Tyrosine kinase]]


==Reference==
==Reference==
Discovery and SAR of novel 4-thiazolyl-2-phenylaminopyrimidines as potent inhibitors of spleen tyrosine kinase (SYK)., Farmer LJ, Bemis G, Britt SD, Cochran J, Connors M, Harrington EM, Hoock T, Markland W, Nanthakumar S, Taslimi P, Ter Haar E, Wang J, Zhaveri D, Salituro FG, Bioorg Med Chem Lett. 2008 Dec 1;18(23):6231-5. Epub 2008 Oct 7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18938080 18938080]
<ref group="xtra">PMID:018938080</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Haar, E Ter.]]
[[Category: Haar, E Ter.]]
[[Category: Alternative splicing]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Host-virus interaction]]
[[Category: Host-virus interaction]]
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[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Sh2 domain]]
[[Category: Sh2 domain]]
[[Category: Syk]]
[[Category: Syk]]
[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]
[[Category: Ubl conjugation]]
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Retrieved from "https://proteopedia.org/3emg"