1w96: Difference between revisions

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New page: left|200px<br /> <applet load="1w96" size="450" color="white" frame="true" align="right" spinBox="true" caption="1w96, resolution 1.80Å" /> '''CRYSTAL STRUCTURE O...
 
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==About this Structure==
==About this Structure==
1W96 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]] with S1A as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.4.1.2 6.4.1.2]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1W96 OCA]].  
1W96 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]] with S1A as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/Acetyl-CoA_carboxylase Acetyl-CoA carboxylase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.4.1.2 6.4.1.2]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1W96 OCA]].  


==Reference==
==Reference==
A mechanism for the potent inhibition of eukaryotic acetyl-coenzyme A carboxylase by soraphen A, a macrocyclic polyketide natural product., Shen Y, Volrath SL, Weatherly SC, Elich TD, Tong L, Mol Cell. 2004 Dec 22;16(6):881-91. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15610732 15610732]
A mechanism for the potent inhibition of eukaryotic acetyl-coenzyme A carboxylase by soraphen A, a macrocyclic polyketide natural product., Shen Y, Volrath SL, Weatherly SC, Elich TD, Tong L, Mol Cell. 2004 Dec 22;16(6):881-91. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15610732 15610732]
[[Category: Acetyl-CoA carboxylase]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: structure-based drug design]]
[[Category: structure-based drug design]]


''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Oct 29 21:21:59 2007''
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 13:57:43 2007''