3fqf: Difference between revisions
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===Staphylococcus aureus F98Y mutant dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-[3-(3,4,5-trimethoxyphenyl)pent-1-ynyl]-6-methylpyrimidine (UCP115A)=== | |||
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{{ABSTRACT_PUBMED_19249312}} | |||
==About this Structure== | |||
3FQF is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_rf122 Staphylococcus aureus rf122]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FQF OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:19249312</ref><references group="xtra"/> | |||
[[Category: Dihydrofolate reductase]] | |||
[[Category: Staphylococcus aureus rf122]] | |||
[[Category: Anderson, A C.]] | |||
[[Category: Frey, K M.]] | |||
[[Category: Liu, J.]] | |||
[[Category: Lombardo, M N.]] | |||
[[Category: Oxidoreductase]] | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 25 12:32:47 2009'' | |||
Revision as of 10:32, 25 March 2009
Staphylococcus aureus F98Y mutant dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-[3-(3,4,5-trimethoxyphenyl)pent-1-ynyl]-6-methylpyrimidine (UCP115A)
Template:ABSTRACT PUBMED 19249312
About this Structure
3FQF is a 1 chain structure of sequence from Staphylococcus aureus rf122. Full crystallographic information is available from OCA.
Reference
- Frey KM, Liu J, Lombardo MN, Bolstad DB, Wright DL, Anderson AC. Crystal structures of wild-type and mutant methicillin-resistant Staphylococcus aureus dihydrofolate reductase reveal an alternate conformation of NADPH that may be linked to trimethoprim resistance. J Mol Biol. 2009 Apr 17;387(5):1298-308. Epub 2009 Feb 26. PMID:19249312 doi:10.1016/j.jmb.2009.02.045
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