Aconitase: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Ralf Stephan (talk | contribs) New page: == glpT family of transporters == The glpT family of transporters consist of several transport proteins from bacteria like ''E. coli'' and ''Salmonella typhimurium'', but also the human gl... |
Ralf Stephan (talk | contribs) No edit summary |
||
| Line 1: | Line 1: | ||
'''Rocker-switch type Major Facilitator antiporters''' are membrane proteins that facilitate both influx and outflux of specific small molecules in a way that is neither the passive letting-through of channels, nor the active pumping of ATPases. They tilt between the two states 'outside open' and 'inside open' and the tilting (or switching) movement does the transport if a molecule has docked beforehand. We call them antiport because, with the second switching back, usually a second, different, molecule is transported in the opposite direction. | |||
The glpT | |||
The glpT subfamily of transporters consist of several transport proteins from bacteria like ''E. coli'' and ''Salmonella typhimurium'', but also the human glucose-6-phosphate translocase. They all are evolutionary connected and have 12 transmembrane helices that stand together to make an opening between them, like a channel. This channel, however, is closed for any molecule in the empty configuration of the molecule.<ref>PMID:18537473</ref> | |||
== References == | == References == | ||
<references/> | <references/> | ||
{{STRUCTURE_1pw4 | PDB=1pw4 | SCENE= | {{STRUCTURE_1pw4 | PDB=1pw4 | SCENE=User:Ralf Stephan/Scenes/Sandbox }} | ||
