3co9: Difference between revisions

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{{Seed}}
[[Image:3co9.png|left|200px]]
[[Image:3co9.jpg|left|200px]]


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{{STRUCTURE_3co9|  PDB=3co9  |  SCENE=  }}  
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===Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor===
===Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor===


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{{ABSTRACT_PUBMED_18487044}}
{{ABSTRACT_PUBMED_18487044}}


==About this Structure==
==About this Structure==
3CO9 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CO9 OCA].  
[[3co9]] is a 2 chain structure of [[RNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CO9 OCA].  
 
==See Also==
*[[RNA polymerase|RNA polymerase]]


==Reference==
==Reference==
<ref group="xtra">PMID:18487044</ref><references group="xtra"/>
<ref group="xtra">PMID:018487044</ref><references group="xtra"/>
[[Category: RNA-directed RNA polymerase]]
[[Category: RNA-directed RNA polymerase]]
[[Category: Viruses]]
[[Category: Viruses]]
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[[Category: Transcription]]
[[Category: Transcription]]
[[Category: Transferase]]
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 11 12:39:47 2009''

Revision as of 14:17, 26 July 2012

File:3co9.png

Template:STRUCTURE 3co9

Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor

Template:ABSTRACT PUBMED 18487044

About this Structure

3co9 is a 2 chain structure of RNA polymerase with sequence from Viruses. Full crystallographic information is available from OCA.

See Also

Reference

  1. Ruebsam F, Webber SE, Tran MT, Tran CV, Murphy DE, Zhao J, Dragovich PS, Kim SH, Li LS, Zhou Y, Han Q, Kissinger CR, Showalter RE, Lardy M, Shah AM, Tsan M, Patel R, Lebrun LA, Kamran R, Sergeeva MV, Bartkowski DM, Nolan TG, Norris DA, Kirkovsky L. Pyrrolo[1,2-b]pyridazin-2-ones as potent inhibitors of HCV NS5B polymerase. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3616-21. Epub 2008 May 1. PMID:18487044 doi:10.1016/j.bmcl.2008.04.066

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