3faa: Difference between revisions

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{{Seed}}
[[Image:3faa.png|left|200px]]
[[Image:3faa.png|left|200px]]


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{{STRUCTURE_3faa|  PDB=3faa  |  SCENE=  }}  
{{STRUCTURE_3faa|  PDB=3faa  |  SCENE=  }}  


===Crystal structure of TGFbRI complexed with a 2-aminoimidazole inhibitor===
===Crystal structure of TGFbRI complexed with a 2-aminoimidazole inhibitor===


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{{ABSTRACT_PUBMED_19135364}}
{{ABSTRACT_PUBMED_19135364}}
==Disease==
Known disease associated with this structure: Loeys-Dietz syndrome, type 1A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190181 190181]], Loeys-Dietz syndrome, type 2A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190181 190181]]


==About this Structure==
==About this Structure==
3FAA is a 5 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FAA OCA].  
[[3faa]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FAA OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:19135364</ref><references group="xtra"/>
<ref group="xtra">PMID:019135364</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein serine/threonine kinase]]
[[Category: Receptor protein serine/threonine kinase]]
Line 42: Line 27:
[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Protein-inhibitor complex]]
[[Category: Protein-inhibitor complex]]
[[Category: Receptor]]
[[Category: Receptor]]
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[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Transmembrane]]
[[Category: Transmembrane]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Feb 15 08:48:13 2009''

Revision as of 11:07, 13 February 2013

File:3faa.png

Template:STRUCTURE 3faa

Crystal structure of TGFbRI complexed with a 2-aminoimidazole inhibitor

Template:ABSTRACT PUBMED 19135364

About this Structure

3faa is a 5 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Bonafoux D, Chuaqui C, Boriack-Sjodin PA, Fitch C, Hankins G, Josiah S, Black C, Hetu G, Ling L, Lee WC. 2-Aminoimidazoles inhibitors of TGF-beta receptor 1. Bioorg Med Chem Lett. 2009 Feb 1;19(3):912-6. Epub 2008 Dec 11. PMID:19135364 doi:10.1016/j.bmcl.2008.11.119

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