2uxx: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[2uxx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UXX OCA]. | |||
==Reference== | ==Reference== | ||
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[[Category: Nucleosome]] | [[Category: Nucleosome]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
[[Category: Oxidoreductase/repressor]] | |||
[[Category: Oxidoreductase/repressor complex]] | [[Category: Oxidoreductase/repressor complex]] | ||
[[Category: Phosphorylation]] | [[Category: Phosphorylation]] | ||
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[[Category: Transcription regulation]] | [[Category: Transcription regulation]] | ||
[[Category: Tranylcypromine]] | [[Category: Tranylcypromine]] | ||
Revision as of 18:28, 14 March 2011
HUMAN LSD1 HISTONE DEMETHYLASE-COREST IN COMPLEX WITH AN FAD-TRANYLCYPROMINE ADDUCT
Template:ABSTRACT PUBMED 17569509
About this Structure
2uxx is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Yang M, Culhane JC, Szewczuk LM, Jalili P, Ball HL, Machius M, Cole PA, Yu H. Structural basis for the inhibition of the LSD1 histone demethylase by the antidepressant trans-2-phenylcyclopropylamine. Biochemistry. 2007 Jul 10;46(27):8058-65. Epub 2007 Jun 15. PMID:17569509 doi:10.1021/bi700664y
- Yang M, Gocke CB, Luo X, Borek D, Tomchick DR, Machius M, Otwinowski Z, Yu H. Structural basis for CoREST-dependent demethylation of nucleosomes by the human LSD1 histone demethylase. Mol Cell. 2006 Aug 4;23(3):377-87. PMID:16885027 doi:https://dx.doi.org/10.1016/j.molcel.2006.07.012
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Cole, P A.
- Culhane, J C.
- Machius, M.
- Yang, M.
- Yu, H.
- Alternative splicing
- Chromatin demethylation
- Chromatin regulator
- Coiled coil
- Corest
- Depression
- Fad
- Histone demethylase
- Host-virus interaction
- Lsd1
- Nuclear protein
- Nucleosome
- Oxidoreductase
- Oxidoreductase/repressor
- Oxidoreductase/repressor complex
- Phosphorylation
- Repressor
- Transcription
- Transcription regulation
- Tranylcypromine