2hd1: Difference between revisions

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{{Seed}}
[[Image:2hd1.png|left|200px]]
[[Image:2hd1.png|left|200px]]


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{{STRUCTURE_2hd1|  PDB=2hd1  |  SCENE=  }}  
{{STRUCTURE_2hd1|  PDB=2hd1  |  SCENE=  }}  


===Crystal structure of PDE9 in complex with IBMX===
===Crystal structure of PDE9 in complex with IBMX===


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{{ABSTRACT_PUBMED_15210993}}
{{ABSTRACT_PUBMED_15210993}}


==Disease==
==About this Structure==
Known disease associated with this structure: Epilepsy, pyridoxine-dependent OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=107323 107323]]
[[2hd1]] is a 2 chain structure of [[Phosphodiesterase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1tbm 1tbm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HD1 OCA].


==About this Structure==
==See Also==
2HD1 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1tbm 1tbm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HD1 OCA].
*[[Phosphodiesterase|Phosphodiesterase]]


==Reference==
==Reference==
<ref group="xtra">PMID:15210993</ref><references group="xtra"/>
<ref group="xtra">PMID:015210993</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Colman, R W.]]
[[Category: Colman, R W.]]
Line 35: Line 23:
[[Category: Zhang, W.]]
[[Category: Zhang, W.]]
[[Category: Cgmp]]
[[Category: Cgmp]]
[[Category: Hydrolase]]
[[Category: Ibmx]]
[[Category: Ibmx]]
[[Category: Pde9]]
[[Category: Pde9]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 10:28:39 2009''

Revision as of 09:50, 25 July 2012

File:2hd1.png

Template:STRUCTURE 2hd1

Crystal structure of PDE9 in complex with IBMX

Template:ABSTRACT PUBMED 15210993

About this Structure

2hd1 is a 2 chain structure of Phosphodiesterase with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 1tbm. Full crystallographic information is available from OCA.

See Also

Reference

  1. Huai Q, Wang H, Zhang W, Colman RW, Robinson H, Ke H. Crystal structure of phosphodiesterase 9 shows orientation variation of inhibitor 3-isobutyl-1-methylxanthine binding. Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9624-9. Epub 2004 Jun 21. PMID:15210993 doi:10.1073/pnas.0401120101

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