1gi2: Difference between revisions
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[[Image:1gi2.png|left|200px]] | [[Image:1gi2.png|left|200px]] | ||
{{STRUCTURE_1gi2| PDB=1gi2 | SCENE= }} | {{STRUCTURE_1gi2| PDB=1gi2 | SCENE= }} | ||
===A NOVEL SERINE PROTEASE INHIBITION MOTIF INVOLVING A MULTI-CENTERED SHORT HYDROGEN BONDING NETWORK AT THE ACTIVE SITE=== | ===A NOVEL SERINE PROTEASE INHIBITION MOTIF INVOLVING A MULTI-CENTERED SHORT HYDROGEN BONDING NETWORK AT THE ACTIVE SITE=== | ||
{{ABSTRACT_PUBMED_11292354}} | {{ABSTRACT_PUBMED_11292354}} | ||
==About this Structure== | ==About this Structure== | ||
[[1gi2]] is a 1 chain structure of [[Trypsin]] with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GI2 OCA]. | |||
==See Also== | |||
*[[Trypsin|Trypsin]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:011292354</ref><references group="xtra"/> | ||
[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
[[Category: Trypsin]] | [[Category: Trypsin]] | ||
| Line 42: | Line 33: | ||
[[Category: Verner, E.]] | [[Category: Verner, E.]] | ||
[[Category: Young, W.]] | [[Category: Young, W.]] | ||
[[Category: Hydrolase]] | |||
[[Category: Oxyanion hole water]] | [[Category: Oxyanion hole water]] | ||
[[Category: Shift of pka of his57]] | [[Category: Shift of pka of his57]] | ||
| Line 52: | Line 44: | ||
[[Category: Very short hydrogen bond]] | [[Category: Very short hydrogen bond]] | ||
[[Category: Zn+2-mediated inhibition]] | [[Category: Zn+2-mediated inhibition]] | ||
Revision as of 09:52, 25 July 2012
A NOVEL SERINE PROTEASE INHIBITION MOTIF INVOLVING A MULTI-CENTERED SHORT HYDROGEN BONDING NETWORK AT THE ACTIVE SITE
Template:ABSTRACT PUBMED 11292354
About this Structure
1gi2 is a 1 chain structure of Trypsin with sequence from Bos taurus. Full crystallographic information is available from OCA.
See Also
Reference
- Katz BA, Elrod K, Luong C, Rice MJ, Mackman RL, Sprengeler PA, Spencer J, Hataye J, Janc J, Link J, Litvak J, Rai R, Rice K, Sideris S, Verner E, Young W. A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site. J Mol Biol. 2001 Apr 13;307(5):1451-86. PMID:11292354 doi:https://dx.doi.org/10.1006/jmbi.2001.4516
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Bos taurus
- Trypsin
- Elrod, K.
- Hatayte, J.
- Janc, J.
- Katz, B A.
- Link, J.
- Litvak, J.
- Luong, C.
- Mackman, R L.
- Rai, R.
- Rice, K.
- Rice, M.
- Sideris, S.
- Spencer, J.
- Sprengeler, P A.
- Verner, E.
- Young, W.
- Hydrolase
- Oxyanion hole water
- Shift of pka of his57
- Specificity
- Structure-based drug design
- Three-centered
- Thrombin
- Urokinase
- Very short hydrogen bond
- Zn+2-mediated inhibition
