2aw1: Difference between revisions

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[[Category: Supuran, C T.]]
[[Category: Supuran, C T.]]
[[Category: Carbonic anhydrase]]
[[Category: Carbonic anhydrase]]
[[Category: Lyase]]
[[Category: Protein-inhibitor complex]]
[[Category: Protein-inhibitor complex]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 11:38:32 2009''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 23 08:12:18 2009''

Revision as of 05:12, 23 September 2009

File:2aw1.png

Template:STRUCTURE 2aw1

Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II "selective" inhibitor Celecoxib

Template:ABSTRACT PUBMED 16290146

About this Structure

2AW1 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Di Fiore A, Pedone C, D'Ambrosio K, Scozzafava A, De Simone G, Supuran CT. Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II "selective" inhibitor celecoxib. Bioorg Med Chem Lett. 2006 Jan 15;16(2):437-42. Epub 2005 Nov 14. PMID:16290146 doi:10.1016/j.bmcl.2005.09.040

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