1xnr: Difference between revisions
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New page: left|200px<br /><applet load="1xnr" size="450" color="white" frame="true" align="right" spinBox="true" caption="1xnr, resolution 3.10Å" /> '''Crystal Structure of... |
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[[Image:1xnr.gif|left|200px]]<br /><applet load="1xnr" size=" | [[Image:1xnr.gif|left|200px]]<br /><applet load="1xnr" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="1xnr, resolution 3.10Å" /> | caption="1xnr, resolution 3.10Å" /> | ||
'''Crystal Structure of an Inosine-Cytosine Wobble Base Pair in the Context of the Decoding Center'''<br /> | '''Crystal Structure of an Inosine-Cytosine Wobble Base Pair in the Context of the Decoding Center'''<br /> | ||
==Overview== | ==Overview== | ||
Here we report the crystal structures of I.C and I.A wobble base pairs in | Here we report the crystal structures of I.C and I.A wobble base pairs in the context of the ribosomal decoding center, clearly showing that the I.A base pair is of an I(anti).A(anti) conformation, as predicted by Crick. Additionally, the structures enable the observation of changes in the anticodon to allow purine-purine base pairing, the 'widest' base pair geometry allowed in the wobble position. | ||
==About this Structure== | ==About this Structure== | ||
1XNR is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with PAR, MG and ZN as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http:// | 1XNR is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with <scene name='pdbligand=PAR:'>PAR</scene>, <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=ZN:'>ZN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XNR OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: Thermus thermophilus]] | [[Category: Thermus thermophilus]] | ||
[[Category: Murphy, F | [[Category: Murphy, F V.]] | ||
[[Category: Ramakrishnan, V.]] | [[Category: Ramakrishnan, V.]] | ||
[[Category: MG]] | [[Category: MG]] | ||
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[[Category: trna modification]] | [[Category: trna modification]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:56:46 2008'' | ||
