1j3k: Difference between revisions
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[[Image:1j3k.png|left|200px]] | [[Image:1j3k.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
[[1j3k]] is a 4 chain structure of [[Dihydrofolate reductase]] with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J3K OCA]. | |||
==See Also== | |||
*[[Dihydrofolate reductase]] | |||
==Reference== | ==Reference== | ||
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[[Category: Yuvaniyama, J.]] | [[Category: Yuvaniyama, J.]] | ||
[[Category: Bifunctional]] | [[Category: Bifunctional]] | ||
[[Category: Oxidoreductase]] | |||
[[Category: Transferase]] | |||
Revision as of 01:00, 27 December 2010
Quadruple mutant (N51I+C59R+S108N+I164L) Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with WR99210, NADPH, and dUMP
Template:ABSTRACT PUBMED 12704428
About this Structure
1j3k is a 4 chain structure of Dihydrofolate reductase with sequence from Plasmodium falciparum. Full crystallographic information is available from OCA.
See Also
Reference
- Yuvaniyama J, Chitnumsub P, Kamchonwongpaisan S, Vanichtanankul J, Sirawaraporn W, Taylor P, Walkinshaw MD, Yuthavong Y. Insights into antifolate resistance from malarial DHFR-TS structures. Nat Struct Biol. 2003 May;10(5):357-65. PMID:12704428 doi:10.1038/nsb921
