1xy1: Difference between revisions
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New page: left|200px<br /><applet load="1xy1" size="450" color="white" frame="true" align="right" spinBox="true" caption="1xy1, resolution 1.04Å" /> '''CRYSTAL STRUCTURE AN... |
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[[Image:1xy1.jpg|left|200px]]<br /><applet load="1xy1" size=" | [[Image:1xy1.jpg|left|200px]]<br /><applet load="1xy1" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="1xy1, resolution 1.04Å" /> | caption="1xy1, resolution 1.04Å" /> | ||
'''CRYSTAL STRUCTURE ANALYSIS OF DEAMINO-OXYTOCIN. CONFORMATIONAL FLEXIBILITY AND RECEPTOR BINDING'''<br /> | '''CRYSTAL STRUCTURE ANALYSIS OF DEAMINO-OXYTOCIN. CONFORMATIONAL FLEXIBILITY AND RECEPTOR BINDING'''<br /> | ||
==Overview== | ==Overview== | ||
Two crystal structures of deamino-oxytocin have been determined at better | Two crystal structures of deamino-oxytocin have been determined at better than 1.1A resolution from isomorphous replacement and anomalous scattering x-ray measurements. In each of two crystal forms there are two closely related conformers with disulfide bridges of different chirality, which may be important in receptor recognition and activation. | ||
==About this Structure== | ==About this Structure== | ||
1XY1 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ] with NH2 as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http:// | 1XY1 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ] with <scene name='pdbligand=NH2:'>NH2</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XY1 OCA]. | ||
==Reference== | ==Reference== | ||
Crystal structure analysis of deamino-oxytocin: conformational flexibility and receptor binding., Wood SP, Tickle IJ, Treharne AM, Pitts JE, Mascarenhas Y, Li JY, Husain J, Cooper S, Blundell TL, Hruby VJ, et al., Science. 1986 May 2;232(4750):633-6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=3008332 3008332] | Crystal structure analysis of deamino-oxytocin: conformational flexibility and receptor binding., Wood SP, Tickle IJ, Treharne AM, Pitts JE, Mascarenhas Y, Li JY, Husain J, Cooper S, Blundell TL, Hruby VJ, et al., Science. 1986 May 2;232(4750):633-6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=3008332 3008332] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: Blundell, T | [[Category: Blundell, T L.]] | ||
[[Category: Cooper, S.]] | [[Category: Cooper, S.]] | ||
[[Category: Husain, J.]] | [[Category: Husain, J.]] | ||
[[Category: Pitts, J | [[Category: Pitts, J E.]] | ||
[[Category: Tickle, I | [[Category: Tickle, I J.]] | ||
[[Category: Wood, S | [[Category: Wood, S P.]] | ||
[[Category: NH2]] | [[Category: NH2]] | ||
[[Category: hormone]] | [[Category: hormone]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:59:57 2008'' | ||
