2gs0: Difference between revisions

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{{Seed}}
[[Image:2gs0.png|left|200px]]
[[Image:2gs0.png|left|200px]]


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{{STRUCTURE_2gs0|  PDB=2gs0  |  SCENE=  }}  
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===NMR structure of the complex between the PH domain of the Tfb1 subunit from TFIIH and the activation domain of p53===
===NMR structure of the complex between the PH domain of the Tfb1 subunit from TFIIH and the activation domain of p53===


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{{ABSTRACT_PUBMED_16793543}}
{{ABSTRACT_PUBMED_16793543}}


==Disease==
==About this Structure==
Known disease associated with this structure: Adrenal cortical carcinoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Breast cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Choroid plexus papilloma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Colorectal cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Hepatocellular carcinoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Li-Fraumeni syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Li-Fraumeni-like syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Nasopharyngeal carcinoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Osteosarcoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Pancreatic cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]]
[[2gs0]] is a 2 chain structure of [[P53]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GS0 OCA].  


==About this Structure==
==See Also==
2GS0 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GS0 OCA].
*[[P53|P53]]


==Reference==
==Reference==
<ref group="xtra">PMID:16793543</ref><references group="xtra"/>
<ref group="xtra">PMID:016793543</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Tfiih]]
[[Category: Tfiih]]
[[Category: Transcription]]
[[Category: Transcription]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 14:51:10 2009''

Revision as of 15:17, 25 July 2012

File:2gs0.png

Template:STRUCTURE 2gs0

NMR structure of the complex between the PH domain of the Tfb1 subunit from TFIIH and the activation domain of p53

Template:ABSTRACT PUBMED 16793543

About this Structure

2gs0 is a 2 chain structure of P53 with sequence from Homo sapiens and Saccharomyces cerevisiae. Full experimental information is available from OCA.

See Also

Reference

  1. Di Lello P, Jenkins LM, Jones TN, Nguyen BD, Hara T, Yamaguchi H, Dikeakos JD, Appella E, Legault P, Omichinski JG. Structure of the Tfb1/p53 complex: Insights into the interaction between the p62/Tfb1 subunit of TFIIH and the activation domain of p53. Mol Cell. 2006 Jun 23;22(6):731-40. PMID:16793543 doi:https://dx.doi.org/10.1016/j.molcel.2006.05.007

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