1zom: Difference between revisions

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{{Seed}}
[[Image:1zom.png|left|200px]]
[[Image:1zom.png|left|200px]]


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{{STRUCTURE_1zom|  PDB=1zom  |  SCENE=  }}  
{{STRUCTURE_1zom|  PDB=1zom  |  SCENE=  }}  


===Crystal Structure of the Catalytic Domain of Coagulation Factor XI in complex with a peptidomimetic Inhibitor===
===Crystal Structure of the Catalytic Domain of Coagulation Factor XI in complex with a peptidomimetic Inhibitor===


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{{ABSTRACT_PUBMED_17181160}}
{{ABSTRACT_PUBMED_17181160}}


==Disease==
==About this Structure==
Known disease associated with this structure: Factor XI deficiency, autosomal dominant OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=264900 264900]], Factor XI deficiency, autosomal recessive OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=264900 264900]]
[[1zom]] is a 1 chain structure of [[Factor XIa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZOM OCA].


==About this Structure==
==See Also==
1ZOM is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZOM OCA].
*[[Factor XIa|Factor XIa]]


==Reference==
==Reference==
<ref group="xtra">PMID:17181160</ref><references group="xtra"/>
<ref group="xtra">PMID:017181160</ref><references group="xtra"/>
[[Category: Coagulation factor XIa]]
[[Category: Coagulation factor XIa]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Rynkiewicz, M.]]
[[Category: Rynkiewicz, M.]]
[[Category: Fxia]]
[[Category: Fxia]]
[[Category: Hydrolase]]
[[Category: Inhibitor]]
[[Category: Inhibitor]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 16:17:11 2009''

Revision as of 17:23, 25 July 2012

File:1zom.png

Template:STRUCTURE 1zom

Crystal Structure of the Catalytic Domain of Coagulation Factor XI in complex with a peptidomimetic Inhibitor

Template:ABSTRACT PUBMED 17181160

About this Structure

1zom is a 1 chain structure of Factor XIa with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Lin J, Deng H, Jin L, Pandey P, Quinn J, Cantin S, Rynkiewicz MJ, Gorga JC, Bibbins F, Celatka CA, Nagafuji P, Bannister TD, Meyers HV, Babine RE, Hayward NJ, Weaver D, Benjamin H, Stassen F, Abdel-Meguid SS, Strickler JE. Design, synthesis, and biological evaluation of peptidomimetic inhibitors of factor XIa as novel anticoagulants. J Med Chem. 2006 Dec 28;49(26):7781-91. PMID:17181160 doi:10.1021/jm060978s

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