3cj2: Difference between revisions
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[[Image:3cj2.png|left|200px]] | [[Image:3cj2.png|left|200px]] | ||
{{STRUCTURE_3cj2| PDB=3cj2 | SCENE= }} | {{STRUCTURE_3cj2| PDB=3cj2 | SCENE= }} | ||
===Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments=== | ===Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments=== | ||
{{ABSTRACT_PUBMED_18400495}} | {{ABSTRACT_PUBMED_18400495}} | ||
==About this Structure== | ==About this Structure== | ||
[[3cj2]] is a 2 chain structure of [[RNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1b Hepatitis c virus subtype 1b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CJ2 OCA]. | |||
==See Also== | |||
*[[RNA polymerase|RNA polymerase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:018400495</ref><references group="xtra"/> | ||
[[Category: Hepatitis c virus subtype 1b]] | [[Category: Hepatitis c virus subtype 1b]] | ||
[[Category: RNA-directed RNA polymerase]] | [[Category: RNA-directed RNA polymerase]] | ||
[[Category: Kissinger, c.]] | [[Category: Kissinger, c.]] | ||
[[Category: Apoptosis]] | [[Category: Apoptosis]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Capsid protein]] | [[Category: Capsid protein]] | ||
[[Category: Drug discovery]] | [[Category: Drug discovery]] | ||
[[Category: Endoplasmic reticulum]] | [[Category: Endoplasmic reticulum]] | ||
| Line 68: | Line 57: | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Viral nucleoprotein]] | [[Category: Viral nucleoprotein]] | ||
[[Category: Virion]] | [[Category: Virion]] | ||
Revision as of 17:47, 25 July 2012
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
Template:ABSTRACT PUBMED 18400495
About this Structure
3cj2 is a 2 chain structure of RNA polymerase with sequence from Hepatitis c virus subtype 1b. Full crystallographic information is available from OCA.
See Also
Reference
- Antonysamy SS, Aubol B, Blaney J, Browner MF, Giannetti AM, Harris SF, Hebert N, Hendle J, Hopkins S, Jefferson E, Kissinger C, Leveque V, Marciano D, McGee E, Najera I, Nolan B, Tomimoto M, Torres E, Wright T. Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors. Bioorg Med Chem Lett. 2008 May 1;18(9):2990-5. Epub 2008 Mar 22. PMID:18400495 doi:https://dx.doi.org/10.1016/j.bmcl.2008.03.056
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Hepatitis c virus subtype 1b
- RNA-directed RNA polymerase
- Kissinger, c.
- Apoptosis
- Atp-binding
- Capsid protein
- Drug discovery
- Endoplasmic reticulum
- Envelope protein
- Fragment based
- Fusion protein
- Glycoprotein
- Hcv ns5b
- Helicase
- Host-virus interaction
- Hydrolase
- Interferon antiviral system evasion
- Lipid droplet
- Lipoprotein
- Membrane
- Metal-binding
- Mitochondrion
- Multifunctional enzyme
- Nucleotide-binding
- Nucleotidyltransferase
- Nucleus
- Oncogene
- Palmitate
- Phosphoprotein
- Protease
- Ribonucleoprotein
- Rna replication
- Rna-binding
- Rna-directed rna polymerase
- Secreted
- Serine protease
- Sh3-binding
- Thiol protease
- Transcription
- Transcription regulation
- Transferase
- Transmembrane
- Viral nucleoprotein
- Virion
