1t84: Difference between revisions
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[[Image:1t84.png|left|200px]] | [[Image:1t84.png|left|200px]] | ||
{{STRUCTURE_1t84| PDB=1t84 | SCENE= }} | {{STRUCTURE_1t84| PDB=1t84 | SCENE= }} | ||
===Solution structure of the Wiskott-Aldrich Syndrome Protein (WASP) autoinhibited core domain complexed with (S)-wiskostatin, a small molecule inhibitor=== | ===Solution structure of the Wiskott-Aldrich Syndrome Protein (WASP) autoinhibited core domain complexed with (S)-wiskostatin, a small molecule inhibitor=== | ||
{{ABSTRACT_PUBMED_15235593}} | {{ABSTRACT_PUBMED_15235593}} | ||
==About this Structure== | ==About this Structure== | ||
[[1t84]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T84 OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:015235593</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Bickford, L C.]] | [[Category: Bickford, L C.]] | ||
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[[Category: Alpha helix]] | [[Category: Alpha helix]] | ||
[[Category: Beta-hairpin turn]] | [[Category: Beta-hairpin turn]] | ||
[[Category: Signaling protein]] | |||
Revision as of 12:40, 5 January 2013
Solution structure of the Wiskott-Aldrich Syndrome Protein (WASP) autoinhibited core domain complexed with (S)-wiskostatin, a small molecule inhibitor
Template:ABSTRACT PUBMED 15235593
About this Structure
1t84 is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.
Reference
- Peterson JR, Bickford LC, Morgan D, Kim AS, Ouerfelli O, Kirschner MW, Rosen MK. Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation. Nat Struct Mol Biol. 2004 Aug;11(8):747-55. Epub 2004 Jul 4. PMID:15235593 doi:10.1038/nsmb796