3b2r: Difference between revisions
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[[Image:3b2r.png|left|200px]] | [[Image:3b2r.png|left|200px]] | ||
{{STRUCTURE_3b2r| PDB=3b2r | SCENE= }} | {{STRUCTURE_3b2r| PDB=3b2r | SCENE= }} | ||
===Crystal Structure of PDE5A1 catalytic domain in complex with Vardenafil=== | ===Crystal Structure of PDE5A1 catalytic domain in complex with Vardenafil=== | ||
{{ABSTRACT_PUBMED_17959709}} | {{ABSTRACT_PUBMED_17959709}} | ||
==About this Structure== | ==About this Structure== | ||
[[3b2r]] is a 2 chain structure of [[Phosphodiesterase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B2R OCA]. | |||
==See Also== | |||
*[[Phosphodiesterase|Phosphodiesterase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:017959709</ref><references group="xtra"/> | ||
[[Category: 3',5'-cyclic-GMP phosphodiesterase]] | [[Category: 3',5'-cyclic-GMP phosphodiesterase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Sharron, H F.]] | [[Category: Sharron, H F.]] | ||
[[Category: Allosteric enzyme]] | [[Category: Allosteric enzyme]] | ||
[[Category: Cgmp phosphodiesterase]] | [[Category: Cgmp phosphodiesterase]] | ||
[[Category: Cgmp-binding]] | [[Category: Cgmp-binding]] | ||
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[[Category: Pde5-inhibitor potency]] | [[Category: Pde5-inhibitor potency]] | ||
[[Category: Phosphorylation]] | [[Category: Phosphorylation]] | ||
[[Category: Sildenafil]] | [[Category: Sildenafil]] | ||
[[Category: Vardenafil]] | [[Category: Vardenafil]] | ||
Revision as of 20:15, 25 July 2012
Crystal Structure of PDE5A1 catalytic domain in complex with Vardenafil
Template:ABSTRACT PUBMED 17959709
About this Structure
3b2r is a 2 chain structure of Phosphodiesterase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Wang H, Ye M, Robinson H, Francis SH, Ke H. Conformational variations of both phosphodiesterase-5 and inhibitors provide the structural basis for the physiological effects of vardenafil and sildenafil. Mol Pharmacol. 2008 Jan;73(1):104-10. Epub 2007 Oct 24. PMID:17959709 doi:10.1124/mol.107.040212
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- 3',5'-cyclic-GMP phosphodiesterase
- Homo sapiens
- Hengming, K.
- Howard, R.
- Huanchen, W.
- Mengchun, Y.
- Sharron, H F.
- Allosteric enzyme
- Cgmp phosphodiesterase
- Cgmp-binding
- Hydrolase
- Levitratm.
- Magnesium
- Metal-binding
- Nucleotide-binding
- Pde5-inhibitor potency
- Phosphorylation
- Sildenafil
- Vardenafil
