2fdp: Difference between revisions
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[[Image:2fdp.png|left|200px]] | [[Image:2fdp.png|left|200px]] | ||
{{STRUCTURE_2fdp| PDB=2fdp | SCENE= }} | {{STRUCTURE_2fdp| PDB=2fdp | SCENE= }} | ||
===Crystal structure of beta-secretase complexed with an amino-ethylene inhibitor=== | ===Crystal structure of beta-secretase complexed with an amino-ethylene inhibitor=== | ||
{{ABSTRACT_PUBMED_16451048}} | {{ABSTRACT_PUBMED_16451048}} | ||
==About this Structure== | ==About this Structure== | ||
[[2fdp]] is a 3 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FDP OCA]. | |||
==See Also== | |||
*[[Beta secretase|Beta secretase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:016451048</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
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[[Category: Aspartyl protease]] | [[Category: Aspartyl protease]] | ||
[[Category: Bace]] | [[Category: Bace]] | ||
[[Category: Hydrolase]] | |||
Revision as of 23:28, 25 July 2012
Crystal structure of beta-secretase complexed with an amino-ethylene inhibitor
Template:ABSTRACT PUBMED 16451048
About this Structure
2fdp is a 3 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Yang W, Lu W, Lu Y, Zhong M, Sun J, Thomas AE, Wilkinson JM, Fucini RV, Lam M, Randal M, Shi XP, Jacobs JW, McDowell RS, Gordon EM, Ballinger MD. Aminoethylenes: a tetrahedral intermediate isostere yielding potent inhibitors of the aspartyl protease BACE-1. J Med Chem. 2006 Feb 9;49(3):839-42. PMID:16451048 doi:10.1021/jm0509142
