1h8d: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[1h8d]] is a 3 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H8D OCA]. | |||
==See Also== | |||
*[[Hirudin]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:11493008</ref><references group="xtra"/> | <ref group="xtra">PMID:11493008</ref><ref group="xtra">PMID:8605148</ref><references group="xtra"/> | ||
[[Category: Hirudo medicinalis]] | [[Category: Hirudo medicinalis]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
[[Category: Deadman, J.]] | [[Category: Deadman, J J.]] | ||
[[Category: Dodson, G G.]] | [[Category: Dodson, G G.]] | ||
[[Category: Green, D.]] | [[Category: Green, D S.]] | ||
[[Category: Skordalakes, E.]] | [[Category: Skordalakes, E.]] | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
Revision as of 22:59, 26 December 2010
X-RAY STRUCTURE OF THE HUMAN ALPHA-THROMBIN COMPLEX WITH A TRIPEPTIDE PHOSPHONATE INHIBITOR.
Template:ABSTRACT PUBMED 11493008
About this Structure
1h8d is a 3 chain structure of Hirudin with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Skordalakes E, Dodson GG, Green DS, Goodwin CA, Scully MF, Hudson HR, Kakkar VV, Deadman JJ. Inhibition of human alpha-thrombin by a phosphonate tripeptide proceeds via a metastable pentacoordinated phosphorus intermediate. J Mol Biol. 2001 Aug 17;311(3):549-55. PMID:11493008 doi:10.1006/jmbi.2001.4872
- Bertrand JA, Oleksyszyn J, Kam CM, Boduszek B, Presnell S, Plaskon RR, Suddath FL, Powers JC, Williams LD. Inhibition of trypsin and thrombin by amino(4-amidinophenyl)methanephosphonate diphenyl ester derivatives: X-ray structures and molecular models. Biochemistry. 1996 Mar 12;35(10):3147-55. PMID:8605148 doi:https://dx.doi.org/10.1021/bi9520996
