2v2d: Difference between revisions

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{{Seed}}
[[Image:2v2d.png|left|200px]]
[[Image:2v2d.png|left|200px]]


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{{STRUCTURE_2v2d|  PDB=2v2d  |  SCENE=  }}  
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===THE A178L MUTATION IN THE C-TERMINAL HINGE OF THE FLEXIBLE LOOP-6 OF TRIOSEPHOSPHATE ISOMERASE (TIM) INDUCES A MORE CLOSED CONFORMATION OF THIS HINGE REGION IN DIMERIC AND MONOMERIC TIM===
===THE A178L MUTATION IN THE C-TERMINAL HINGE OF THE FLEXIBLE LOOP-6 OF TRIOSEPHOSPHATE ISOMERASE (TIM) INDUCES A MORE CLOSED CONFORMATION OF THIS HINGE REGION IN DIMERIC AND MONOMERIC TIM===


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{{ABSTRACT_PUBMED_18219118}}
{{ABSTRACT_PUBMED_18219118}}


==About this Structure==
==About this Structure==
2V2D is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V2D OCA].  
[[2v2d]] is a 1 chain structure of [[TIM test]] and [[Triose Phosphate Isomerase]] with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V2D OCA].  
 
==See Also==
*[[TIM test|TIM test]]
*[[Triose Phosphate Isomerase|Triose Phosphate Isomerase]]


==Reference==
==Reference==
<ref group="xtra">PMID:18219118</ref><references group="xtra"/>
<ref group="xtra">PMID:018219118</ref><references group="xtra"/>
[[Category: Triose-phosphate isomerase]]
[[Category: Triose-phosphate isomerase]]
[[Category: Trypanosoma brucei brucei]]
[[Category: Trypanosoma brucei brucei]]
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[[Category: Tim-barrel]]
[[Category: Tim-barrel]]
[[Category: Triosephosphate isomerase]]
[[Category: Triosephosphate isomerase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 23:55:02 2009''

Revision as of 02:33, 26 July 2012

File:2v2d.png

Template:STRUCTURE 2v2d

THE A178L MUTATION IN THE C-TERMINAL HINGE OF THE FLEXIBLE LOOP-6 OF TRIOSEPHOSPHATE ISOMERASE (TIM) INDUCES A MORE CLOSED CONFORMATION OF THIS HINGE REGION IN DIMERIC AND MONOMERIC TIM

Template:ABSTRACT PUBMED 18219118

About this Structure

2v2d is a 1 chain structure of TIM test and Triose Phosphate Isomerase with sequence from Trypanosoma brucei brucei. Full crystallographic information is available from OCA.

See Also

Reference

  1. Alahuhta M, Casteleijn MG, Neubauer P, Wierenga RK. Structural studies show that the A178L mutation in the C-terminal hinge of the catalytic loop-6 of triosephosphate isomerase (TIM) induces a closed-like conformation in dimeric and monomeric TIM. Acta Crystallogr D Biol Crystallogr. 2008 Feb;64(Pt 2):178-88. Epub 2008, Jan 16. PMID:18219118 doi:10.1107/S0907444907059021

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