3cic: Difference between revisions
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[[Image:3cic.png|left|200px]] | [[Image:3cic.png|left|200px]] | ||
{{STRUCTURE_3cic| PDB=3cic | SCENE= }} | {{STRUCTURE_3cic| PDB=3cic | SCENE= }} | ||
===Structure of BACE Bound to SCH709583=== | ===Structure of BACE Bound to SCH709583=== | ||
{{ABSTRACT_PUBMED_18468890}} | {{ABSTRACT_PUBMED_18468890}} | ||
==About this Structure== | ==About this Structure== | ||
[[3cic]] is a 2 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CIC OCA]. | |||
==See Also== | |||
*[[Beta secretase|Beta secretase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:018468890</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
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[[Category: Bace1]] | [[Category: Bace1]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
Revision as of 03:10, 26 July 2012
Structure of BACE Bound to SCH709583
Template:ABSTRACT PUBMED 18468890
About this Structure
3cic is a 2 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Cumming JN, Le TX, Babu S, Carroll C, Chen X, Favreau L, Gaspari P, Guo T, Hobbs DW, Huang Y, Iserloh U, Kennedy ME, Kuvelkar R, Li G, Lowrie J, McHugh NA, Ozgur L, Pan J, Parker EM, Saionz K, Stamford AW, Strickland C, Tadesse D, Voigt J, Wang L, Wu Y, Zhang L, Zhang Q. Rational design of novel, potent piperazinone and imidazolidinone BACE1 inhibitors. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3236-41. Epub 2008 Apr 25. PMID:18468890 doi:https://dx.doi.org/10.1016/j.bmcl.2008.04.050
