1mox: Difference between revisions

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{{Seed}}
[[Image:1mox.png|left|200px]]
[[Image:1mox.png|left|200px]]


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{{STRUCTURE_1mox|  PDB=1mox  |  SCENE=  }}  
{{STRUCTURE_1mox|  PDB=1mox  |  SCENE=  }}  


===Crystal Structure of Human Epidermal Growth Factor Receptor (residues 1-501) in complex with TGF-alpha===
===Crystal Structure of Human Epidermal Growth Factor Receptor (residues 1-501) in complex with TGF-alpha===


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{{ABSTRACT_PUBMED_12297049}}
{{ABSTRACT_PUBMED_12297049}}


==Disease==
==About this Structure==
Known disease associated with this structure: Adenocarcinoma of lung, response to tyrosine kinase inhibitor in OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=131550 131550]], Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=131550 131550]], Nonsmall cell lung cancer, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=131550 131550]]
[[1mox]] is a 4 chain structure of [[Epidermal Growth Factor Receptor]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MOX OCA].


==About this Structure==
==See Also==
1MOX is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MOX OCA].
*[[Epidermal Growth Factor Receptor|Epidermal Growth Factor Receptor]]


==Reference==
==Reference==
<ref group="xtra">PMID:12297049</ref><references group="xtra"/>
<ref group="xtra">PMID:012297049</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Transferase]]
[[Category: Transferase]]
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[[Category: Growth factor]]
[[Category: Growth factor]]
[[Category: Receptor]]
[[Category: Receptor]]
 
[[Category: Transferase-growth factor complex]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 03:43:18 2009''

Revision as of 05:50, 26 July 2012

File:1mox.png

Template:STRUCTURE 1mox

Crystal Structure of Human Epidermal Growth Factor Receptor (residues 1-501) in complex with TGF-alpha

Template:ABSTRACT PUBMED 12297049

About this Structure

1mox is a 4 chain structure of Epidermal Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Garrett TP, McKern NM, Lou M, Elleman TC, Adams TE, Lovrecz GO, Zhu HJ, Walker F, Frenkel MJ, Hoyne PA, Jorissen RN, Nice EC, Burgess AW, Ward CW. Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha. Cell. 2002 Sep 20;110(6):763-73. PMID:12297049

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