2clx: Difference between revisions

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{{Seed}}
[[Image:2clx.png|left|200px]]
[[Image:2clx.png|left|200px]]


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{{STRUCTURE_2clx|  PDB=2clx  |  SCENE=  }}  
{{STRUCTURE_2clx|  PDB=2clx  |  SCENE=  }}  


===4-ARYLAZO-3,5-DIAMINO-1H-PYRAZOLE CDK INHIBITORS: SAR STUDY, CRYSTAL STRUCTURE IN COMPLEX WITH CDK2, SELECTIVITY, AND CELLULAR EFFECTS===
===4-ARYLAZO-3,5-DIAMINO-1H-PYRAZOLE CDK INHIBITORS: SAR STUDY, CRYSTAL STRUCTURE IN COMPLEX WITH CDK2, SELECTIVITY, AND CELLULAR EFFECTS===


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{{ABSTRACT_PUBMED_17064068}}
{{ABSTRACT_PUBMED_17064068}}


==About this Structure==
==About this Structure==
2CLX is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CLX OCA].  
[[2clx]] is a 1 chain structure of [[Cell Division Protein Kinase 2]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CLX OCA].  
 
==See Also==
*[[Cell Division Protein Kinase 2|Cell Division Protein Kinase 2]]


==Reference==
==Reference==
<ref group="xtra">PMID:17064068</ref><references group="xtra"/>
<ref group="xtra">PMID:017064068</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Cankar, P.]]
[[Category: Cankar, P.]]
Line 47: Line 38:
[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
[[Category: Phosphorylation]]
[[Category: Phosphorylation]]
[[Category: Polymorphism]]
[[Category: Serine-threonine-protein kinase]]
[[Category: Serine-threonine-protein kinase]]
[[Category: Serine/threonine- protein kinase]]
[[Category: Serine/threonine- protein kinase]]
[[Category: Transferase]]
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 03:52:21 2009''

Revision as of 06:01, 26 July 2012

File:2clx.png

Template:STRUCTURE 2clx

4-ARYLAZO-3,5-DIAMINO-1H-PYRAZOLE CDK INHIBITORS: SAR STUDY, CRYSTAL STRUCTURE IN COMPLEX WITH CDK2, SELECTIVITY, AND CELLULAR EFFECTS

Template:ABSTRACT PUBMED 17064068

About this Structure

2clx is a 1 chain structure of Cell Division Protein Kinase 2 with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Krystof V, Cankar P, Frysova I, Slouka J, Kontopidis G, Dzubak P, Hajduch M, Srovnal J, de Azevedo WF Jr, Orsag M, Paprskarova M, Rolcik J, Latr A, Fischer PM, Strnad M. 4-arylazo-3,5-diamino-1H-pyrazole CDK inhibitors: SAR study, crystal structure in complex with CDK2, selectivity, and cellular effects. J Med Chem. 2006 Nov 2;49(22):6500-9. PMID:17064068 doi:10.1021/jm0605740

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