3c4c: Difference between revisions

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{{Seed}}
[[Image:3c4c.png|left|200px]]
[[Image:3c4c.png|left|200px]]


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{{STRUCTURE_3c4c|  PDB=3c4c  |  SCENE=  }}  
{{STRUCTURE_3c4c|  PDB=3c4c  |  SCENE=  }}  


===B-Raf Kinase in Complex with PLX4720===
===B-Raf Kinase in Complex with PLX4720===


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{{ABSTRACT_PUBMED_18287029}}
{{ABSTRACT_PUBMED_18287029}}


==About this Structure==
==About this Structure==
3C4C is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C4C OCA].  
[[3c4c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C4C OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:18287029</ref><references group="xtra"/>
<ref group="xtra">PMID:018287029</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Braf]]
[[Category: Braf]]
[[Category: Cardiomyopathy]]
[[Category: Cardiomyopathy]]
[[Category: Cytoplasm]]
[[Category: Disease mutation]]
[[Category: Disease mutation]]
[[Category: Metal-binding]]
[[Category: Metal-binding]]
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[[Category: Phorbol-ester binding]]
[[Category: Phorbol-ester binding]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Proto-oncogene]]
[[Category: Proto-oncogene]]
[[Category: Raf]]
[[Category: Raf]]
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[[Category: Serine/threonine-protein kinase]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Zinc]]
[[Category: Zinc-finger]]
[[Category: Zinc-finger]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 04:11:12 2009''

Revision as of 17:48, 7 January 2013

File:3c4c.png

Template:STRUCTURE 3c4c

B-Raf Kinase in Complex with PLX4720

Template:ABSTRACT PUBMED 18287029

About this Structure

3c4c is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Tsai J, Lee JT, Wang W, Zhang J, Cho H, Mamo S, Bremer R, Gillette S, Kong J, Haass NK, Sproesser K, Li L, Smalley KS, Fong D, Zhu YL, Marimuthu A, Nguyen H, Lam B, Liu J, Cheung I, Rice J, Suzuki Y, Luu C, Settachatgul C, Shellooe R, Cantwell J, Kim SH, Schlessinger J, Zhang KY, West BL, Powell B, Habets G, Zhang C, Ibrahim PN, Hirth P, Artis DR, Herlyn M, Bollag G. Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):3041-6. Epub 2008 Feb 19. PMID:18287029

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