3bht: Difference between revisions
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[[Image:3bht.png|left|200px]] | [[Image:3bht.png|left|200px]] | ||
{{STRUCTURE_3bht| PDB=3bht | SCENE= }} | {{STRUCTURE_3bht| PDB=3bht | SCENE= }} | ||
===Structure of phosphorylated Thr160 CDK2/cyclin A in complex with the inhibitor meriolin 3=== | ===Structure of phosphorylated Thr160 CDK2/cyclin A in complex with the inhibitor meriolin 3=== | ||
{{ABSTRACT_PUBMED_17804748}} | {{ABSTRACT_PUBMED_17804748}} | ||
==About this Structure== | ==About this Structure== | ||
[[3bht]] is a 4 chain structure of [[Cell Division Protein Kinase 2]] and [[Cyclin]] with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BHT OCA]. | |||
==See Also== | |||
*[[Cell Division Protein Kinase 2|Cell Division Protein Kinase 2]] | |||
*[[Cyclin|Cyclin]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:017804748</ref><ref group="xtra">PMID:018232649</ref><references group="xtra"/> | ||
[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
[[Category: Cyclin-dependent kinase]] | [[Category: Cyclin-dependent kinase]] | ||
| Line 47: | Line 39: | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
[[Category: Phosphorylation]] | [[Category: Phosphorylation]] | ||
[[Category: Ser/thr protein kinase]] | [[Category: Ser/thr protein kinase]] | ||
[[Category: Serine/threonine-protein kinase]] | [[Category: Serine/threonine-protein kinase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 07:16, 26 July 2012
Structure of phosphorylated Thr160 CDK2/cyclin A in complex with the inhibitor meriolin 3
Template:ABSTRACT PUBMED 17804748
About this Structure
3bht is a 4 chain structure of Cell Division Protein Kinase 2 and Cyclin with sequence from Bos taurus and Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Bettayeb K, Tirado OM, Marionneau-Lambot S, Ferandin Y, Lozach O, Morris JC, Mateo-Lozano S, Drueckes P, Schachtele C, Kubbutat MH, Liger F, Marquet B, Joseph B, Echalier A, Endicott JA, Notario V, Meijer L. Meriolins, a new class of cell death inducing kinase inhibitors with enhanced selectivity for cyclin-dependent kinases. Cancer Res. 2007 Sep 1;67(17):8325-34. PMID:17804748 doi:67/17/8325
- Echalier A, Bettayeb K, Ferandin Y, Lozach O, Clement M, Valette A, Liger F, Marquet B, Morris JC, Endicott JA, Joseph B, Meijer L. Meriolins (3-(pyrimidin-4-yl)-7-azaindoles): synthesis, kinase inhibitory activity, cellular effects, and structure of a CDK2/cyclin A/meriolin complex. J Med Chem. 2008 Feb 28;51(4):737-51. Epub 2008 Jan 31. PMID:18232649 doi:10.1021/jm700940h
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Bos taurus
- Cyclin-dependent kinase
- Homo sapiens
- Bettayeb, K.
- Clement, M.
- Echalier, A.
- Endicott, J A.
- Ferandin, Y.
- Joseph, B.
- Liger, F.
- Lozach, O.
- Marquet, B.
- Meijer, L.
- Morris, J C.
- Valette, A.
- Atp-binding
- Cell cycle
- Cell division
- Cyclin
- Mitosis
- Nucleotide-binding
- Phosphoprotein
- Phosphorylation
- Ser/thr protein kinase
- Serine/threonine-protein kinase
- Transferase
