2r7g: Difference between revisions

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{{Seed}}
[[Image:2r7g.png|left|200px]]
[[Image:2r7g.png|left|200px]]


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{{STRUCTURE_2r7g|  PDB=2r7g  |  SCENE=  }}  
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===Structure of the retinoblastoma protein pocket domain in complex with adenovirus E1A CR1 domain===
===Structure of the retinoblastoma protein pocket domain in complex with adenovirus E1A CR1 domain===


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{{ABSTRACT_PUBMED_17974914}}
{{ABSTRACT_PUBMED_17974914}}


==Disease==
==About this Structure==
Known disease associated with this structure: Bladder cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=180200 180200]], Osteosarcoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=180200 180200]], Pinealoma with bilateral retinoblastoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=180200 180200]], Retinoblastoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=180200 180200]]
[[2r7g]] is a 5 chain structure of [[Retinoblastoma protein]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_adenovirus_5 Human adenovirus 5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R7G OCA].


==About this Structure==
==See Also==
2R7G is a 5 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_adenovirus_5 Human adenovirus 5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R7G OCA].
*[[Retinoblastoma protein|Retinoblastoma protein]]


==Reference==
==Reference==
<ref group="xtra">PMID:17974914</ref><references group="xtra"/>
<ref group="xtra">PMID:017974914</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Human adenovirus 5]]
[[Category: Human adenovirus 5]]
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[[Category: Retinoblastoma protein]]
[[Category: Retinoblastoma protein]]
[[Category: Transcription repressor]]
[[Category: Transcription repressor]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 04:56:07 2009''

Revision as of 07:22, 26 July 2012

File:2r7g.png

Template:STRUCTURE 2r7g

Structure of the retinoblastoma protein pocket domain in complex with adenovirus E1A CR1 domain

Template:ABSTRACT PUBMED 17974914

About this Structure

2r7g is a 5 chain structure of Retinoblastoma protein with sequence from Homo sapiens and Human adenovirus 5. Full crystallographic information is available from OCA.

See Also

Reference

  1. Liu X, Marmorstein R. Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor. Genes Dev. 2007 Nov 1;21(21):2711-6. PMID:17974914 doi:21/21/2711

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