1t25: Difference between revisions

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[[Category: Vivas, L.]]
[[Category: Vivas, L.]]
[[Category: Winter, V J.]]
[[Category: Winter, V J.]]
[[Category: Oxidoreductase]]
[[Category: Protein-ligand complex]]
[[Category: Protein-ligand complex]]


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Revision as of 11:39, 1 October 2009

File:1t25.png

Template:STRUCTURE 1t25

Plasmodium falciparum lactate dehydrogenase complexed with NADH and 3-hydroxyisoxazole-4-carboxylic acid

Template:ABSTRACT PUBMED 15117937

About this Structure

1T25 is a 1 chain structure of sequence from Plasmodium falciparum. The June 2008 RCSB PDB Molecule of the Month feature on Lactate Dehydrogenase by David S. Goodsell is 10.2210/rcsb_pdb/mom_2008_6. Full crystallographic information is available from OCA.

Reference

  1. Cameron A, Read J, Tranter R, Winter VJ, Sessions RB, Brady RL, Vivas L, Easton A, Kendrick H, Croft SL, Barros D, Lavandera JL, Martin JJ, Risco F, Garcia-Ochoa S, Gamo FJ, Sanz L, Leon L, Ruiz JR, Gabarro R, Mallo A, Gomez de las Heras F. Identification and activity of a series of azole-based compounds with lactate dehydrogenase-directed anti-malarial activity. J Biol Chem. 2004 Jul 23;279(30):31429-39. Epub 2004 Apr 26. PMID:15117937 doi:10.1074/jbc.M402433200

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