2ntr: Difference between revisions
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[[Image:2ntr.png|left|200px]] | [[Image:2ntr.png|left|200px]] | ||
{{STRUCTURE_2ntr| PDB=2ntr | SCENE= }} | {{STRUCTURE_2ntr| PDB=2ntr | SCENE= }} | ||
===Crystal structure of Human Bace-1 bound to inhibitor=== | ===Crystal structure of Human Bace-1 bound to inhibitor=== | ||
{{ABSTRACT_PUBMED_17112725}} | {{ABSTRACT_PUBMED_17112725}} | ||
==About this Structure== | ==About this Structure== | ||
[[2ntr]] is a 1 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NTR OCA]. | |||
==See Also== | |||
*[[Beta secretase|Beta secretase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:017112725</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
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[[Category: Bace]] | [[Category: Bace]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
Revision as of 08:29, 26 July 2012
Crystal structure of Human Bace-1 bound to inhibitor
Template:ABSTRACT PUBMED 17112725
About this Structure
2ntr is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- McGaughey GB, Colussi D, Graham SL, Lai MT, Munshi SK, Nantermet PG, Pietrak B, Rajapakse HA, Selnick HG, Stauffer SR, Holloway MK. Beta-secretase (BACE-1) inhibitors: accounting for 10s loop flexibility using rigid active sites. Bioorg Med Chem Lett. 2007 Feb 15;17(4):1117-21. Epub 2006 Nov 6. PMID:17112725 doi:10.1016/j.bmcl.2006.11.003
