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==About this Structure==
==About this Structure==
1SG1 is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. The August 2005 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Neurotrophins''  by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2005_8 10.2210/rcsb_pdb/mom_2005_8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SG1 OCA].  
1SG1 is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. The August 2005 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Neurotrophins''  by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2005_8 10.2210/rcsb_pdb/mom_2005_8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SG1 OCA].  


==Reference==
==Reference==
Line 29: Line 29:
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Neurotrophins]]
[[Category: Neurotrophins]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Garcia, K C.]]
[[Category: Garcia, K C.]]
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[[Category: Crystal structure]]
[[Category: Crystal structure]]
[[Category: Growth factor receptor]]
[[Category: Growth factor receptor]]
[[Category: Hormone/growth factor/membrane protein complex]]
[[Category: Nerve growth factor]]
[[Category: Nerve growth factor]]
[[Category: Neurotrophin]]
[[Category: Neurotrophin]]
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[[Category: Receptor/ligand complex]]
[[Category: Receptor/ligand complex]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 05:56:19 2009''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 21 09:33:37 2010''

Revision as of 07:33, 21 January 2010

File:1sg1.png

Template:STRUCTURE 1sg1

Crystal Structure of the Receptor-Ligand Complex between Nerve Growth Factor and the Common Neurotrophin Receptor p75

Template:ABSTRACT PUBMED 15131306

Disease

Known disease associated with this structure: Neuropathy, hereditary sensory and autonomic, type V OMIM:[162030]

About this Structure

1SG1 is a 3 chains structure with sequences from Homo sapiens and Rattus norvegicus. The August 2005 RCSB PDB Molecule of the Month feature on Neurotrophins by David S. Goodsell is 10.2210/rcsb_pdb/mom_2005_8. Full crystallographic information is available from OCA.

Reference

  1. He XL, Garcia KC. Structure of nerve growth factor complexed with the shared neurotrophin receptor p75. Science. 2004 May 7;304(5672):870-5. PMID:15131306 doi:10.1126/science.1095190

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