2h08: Difference between revisions

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{{Seed}}
[[Image:2h08.png|left|200px]]
[[Image:2h08.png|left|200px]]


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{{STRUCTURE_2h08|  PDB=2h08  |  SCENE=  }}  
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===crystal structure of human phosphoribosyl pyrophosphate synthetase 1 mutant Y146M===
===crystal structure of human phosphoribosyl pyrophosphate synthetase 1 mutant Y146M===


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{{ABSTRACT_PUBMED_16939420}}
{{ABSTRACT_PUBMED_16939420}}
==Disease==
Known disease associated with this structure: Arts syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=311850 311850]], Charcot-Marie-Tooth disease, X-linked recessive, 5 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=311850 311850]], Gout, PRPS-related OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=311850 311850]], Phosphoribosylpyrophosphate synthetase superactivity OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=311850 311850]]


==About this Structure==
==About this Structure==
2H08 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H08 OCA].  
[[2h08]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H08 OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:16939420</ref><references group="xtra"/>
<ref group="xtra">PMID:016939420</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Ribose-phosphate diphosphokinase]]
[[Category: Ribose-phosphate diphosphokinase]]
Line 36: Line 21:
[[Category: Prpp synthetase 1]]
[[Category: Prpp synthetase 1]]
[[Category: Prs1]]
[[Category: Prs1]]
 
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 05:58:44 2009''

Revision as of 11:53, 7 January 2013

File:2h08.png

Template:STRUCTURE 2h08

crystal structure of human phosphoribosyl pyrophosphate synthetase 1 mutant Y146M

Template:ABSTRACT PUBMED 16939420

About this Structure

2h08 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Li S, Lu Y, Peng B, Ding J. Crystal structure of human phosphoribosylpyrophosphate synthetase 1 reveals a novel allosteric site. Biochem J. 2007 Jan 1;401(1):39-47. PMID:16939420 doi:10.1042/BJ20061066

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