2ate: Difference between revisions
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New page: left|200px<br /><applet load="2ate" size="450" color="white" frame="true" align="right" spinBox="true" caption="2ate, resolution 1.80Å" /> '''Structure of the com... |
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[[Image:2ate.gif|left|200px]]<br /><applet load="2ate" size=" | [[Image:2ate.gif|left|200px]]<br /><applet load="2ate" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="2ate, resolution 1.80Å" /> | caption="2ate, resolution 1.80Å" /> | ||
'''Structure of the complex of PurE with NitroAIR'''<br /> | '''Structure of the complex of PurE with NitroAIR'''<br /> | ||
==Overview== | ==Overview== | ||
Structural studies, sequence alignments, and biochemistry have provided | Structural studies, sequence alignments, and biochemistry have provided new insights into the evolution of the purine biosynthetic pathway. The importance of chemistry, the binding of ribose 5-phosphate (common to all purine biosynthetic intermediates), and transient protein-protein interactions in channeling of chemically unstable intermediates have all been examined in the past few years. | ||
==About this Structure== | ==About this Structure== | ||
2ATE is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with NIA as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Phosphoribosylaminoimidazole_carboxylase Phosphoribosylaminoimidazole carboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.21 4.1.1.21] Full crystallographic information is available from [http:// | 2ATE is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=NIA:'>NIA</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Phosphoribosylaminoimidazole_carboxylase Phosphoribosylaminoimidazole carboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.21 4.1.1.21] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ATE OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: Phosphoribosylaminoimidazole carboxylase]] | [[Category: Phosphoribosylaminoimidazole carboxylase]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Ealick, S | [[Category: Ealick, S E.]] | ||
[[Category: Hoskins, A | [[Category: Hoskins, A A.]] | ||
[[Category: Kappock, T | [[Category: Kappock, T J.]] | ||
[[Category: Mathews, I | [[Category: Mathews, I I.]] | ||
[[Category: Okamoto, A.]] | [[Category: Okamoto, A.]] | ||
[[Category: Peng, P.]] | [[Category: Peng, P.]] | ||
[[Category: Stubbe, J.]] | [[Category: Stubbe, J.]] | ||
[[Category: Zaugg, J | [[Category: Zaugg, J B.]] | ||
[[Category: NIA]] | [[Category: NIA]] | ||
[[Category: nitroair complex]] | [[Category: nitroair complex]] | ||
[[Category: pure]] | [[Category: pure]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:30:51 2008'' | ||
