3cot: Difference between revisions

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{{Seed}}
[[Image:3cot.png|left|200px]]
[[Image:3cot.png|left|200px]]


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{{STRUCTURE_3cot|  PDB=3cot  |  SCENE=  }}  
{{STRUCTURE_3cot|  PDB=3cot  |  SCENE=  }}  


===Crystal structure of human liver delta(4)-3-ketosteroid 5beta-reductase (akr1d1) in complex with progesterone and nadp. Resolution: 2.03 A.===
===Crystal structure of human liver delta(4)-3-ketosteroid 5beta-reductase (akr1d1) in complex with progesterone and nadp. Resolution: 2.03 A.===


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{{ABSTRACT_PUBMED_18407998}}
{{ABSTRACT_PUBMED_18407998}}


==About this Structure==
==About this Structure==
3COT is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3COT OCA].  
[[3cot]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3COT OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:18407998</ref><references group="xtra"/>
<ref group="xtra">PMID:018407998</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Christianson, D W.]]
[[Category: Christianson, D W.]]
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[[Category: 5beta reductase]]
[[Category: 5beta reductase]]
[[Category: Bile acid catabolism]]
[[Category: Bile acid catabolism]]
[[Category: Cytoplasm]]
[[Category: Disease mutation]]
[[Category: Disease mutation]]
[[Category: E120]]
[[Category: E120]]
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[[Category: Steroid c-c double bond reduction]]
[[Category: Steroid c-c double bond reduction]]
[[Category: Steroid metabolism]]
[[Category: Steroid metabolism]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 06:11:33 2009''

Revision as of 19:50, 7 January 2013

File:3cot.png

Template:STRUCTURE 3cot

Crystal structure of human liver delta(4)-3-ketosteroid 5beta-reductase (akr1d1) in complex with progesterone and nadp. Resolution: 2.03 A.

Template:ABSTRACT PUBMED 18407998

About this Structure

3cot is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Di Costanzo L, Drury JE, Penning TM, Christianson DW. Crystal structure of human liver Delta4-3-ketosteroid 5beta-reductase (AKR1D1) and implications for substrate binding and catalysis. J Biol Chem. 2008 Jun 13;283(24):16830-9. Epub 2008 Apr 11. PMID:18407998 doi:https://dx.doi.org/10.1074/jbc.M801778200

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