2vth: Difference between revisions

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===IDENTIFICATION OF N-(4-PIPERIDINYL)-4-(2,6-DICHLOROBENZOYLAMINO)-1H-PYRAZOLE-3-CARBOXAMIDE (AT7519), A NOVEL CYCLIN DEPENDENT KINASE INHIBITOR USING FRAGMENT-BASED X-RAY CRYSTALLOGRAPHY AND STRUCTURE BASED DRUG DESIGN.===

===IDENTIFICATION OF N-(4-PIPERIDINYL)-4-(2,6-DICHLOROBENZOYLAMINO)-1H-PYRAZOLE-3-CARBOXAMIDE (AT7519), A NOVEL CYCLIN DEPENDENT KINASE INHIBITOR USING FRAGMENT-BASED X-RAY CRYSTALLOGRAPHY AND STRUCTURE BASED DRUG DESIGN===

<!--

The line below this paragraph, {{ABSTRACT_PUBMED_18656911}}, adds the Publication Abstract to the page

(as it appears on PubMed at http://www.pubmed.gov), where 18656911 is the PubMed ID number.

-->

==About this Structure==

2VTH is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VTH OCA].

2VTH is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VTH OCA].

==Reference==

[[Category: Homo sapiens]]

[[Category: Berdini, V.]]

Line 33:

Line 42:

[[Category: Saxty, G.]]

[[Category: Seavers, L C.A.]]

[[Category: Smith, D M.]]

[[Category: Smith, D.]]

[[Category: Squires, M S.]]

[[Category: Trewartha, G.]]

[[Category: Walker, M T.]]

[[Category: Woodhead, A J.]]

[[Category: Woolford, A J.A.]]

[[Category: Woolford, A J.]]

[[Category: Wyatt, P G.]]

~~[[Category: Atp-binding]]~~

[[Category: Cell cycle]]

~~[[Category: Cell division]]~~

~~[[Category: Fragment screening]]~~

~~[[Category: Kinase]]~~

[[Category: Mitosis]]

~~[[Category: Nucleotide-binding]]~~

~~[[Category: Phosphoprotein]]~~

~~[[Category: Phosphorylation]]~~

~~[[Category: Polymorphism]]~~

~~[[Category: Protein kinase]]~~

[[Category: Serine/threonine protein kinase]]

~~[[Category: Serine/threonine-protein kinase]]~~

~~[[Category: Structure based drug design]]~~

[[Category: Transferase]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Tue Feb~~ 17 ~~07:56~~:~~07 2009~~''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 3 11:17:45 2010''

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@@ Line 10: / Line 10: @@
 {{STRUCTURE_2vth|  PDB=2vth  |  SCENE=  }}
-===IDENTIFICATION OF N-(4-PIPERIDINYL)-4-(2,6-DICHLOROBENZOYLAMINO)-1H-PYRAZOLE-3-CARBOXAMIDE (AT7519), A NOVEL CYCLIN DEPENDENT KINASE INHIBITOR USING FRAGMENT-BASED X-RAY CRYSTALLOGRAPHY AND STRUCTURE BASED DRUG DESIGN.===
+===IDENTIFICATION OF N-(4-PIPERIDINYL)-4-(2,6-DICHLOROBENZOYLAMINO)-1H-PYRAZOLE-3-CARBOXAMIDE (AT7519), A NOVEL CYCLIN DEPENDENT KINASE INHIBITOR USING FRAGMENT-BASED X-RAY CRYSTALLOGRAPHY AND STRUCTURE BASED DRUG DESIGN===
+<!--
+The line below this paragraph, {{ABSTRACT_PUBMED_18656911}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 18656911 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_18656911}}
 ==About this Structure==
-VTH is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VTH OCA].
+VTH is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VTH OCA].
+==Reference==
+<ref group="xtra">PMID:18656911</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
 [[Category: Berdini, V.]]
@@ Line 33: / Line 42: @@
 [[Category: Saxty, G.]]
 [[Category: Seavers, L C.A.]]
-[[Category: Smith, D M.]]
+[[Category: Smith, D.]]
 [[Category: Squires, M S.]]
 [[Category: Trewartha, G.]]
 [[Category: Walker, M T.]]
 [[Category: Woodhead, A J.]]
-[[Category: Woolford, A J.A.]]
+[[Category: Woolford, A J.]]
 [[Category: Wyatt, P G.]]
-[[Category: Atp-binding]]
 [[Category: Cell cycle]]
-[[Category: Cell division]]
-[[Category: Fragment screening]]
-[[Category: Kinase]]
 [[Category: Mitosis]]
-[[Category: Nucleotide-binding]]
-[[Category: Phosphoprotein]]
-[[Category: Phosphorylation]]
-[[Category: Polymorphism]]
-[[Category: Protein kinase]]
 [[Category: Serine/threonine protein kinase]]
-[[Category: Serine/threonine-protein kinase]]
-[[Category: Structure based drug design]]
 [[Category: Transferase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 07:56:07 2009''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov  3 11:17:45 2010''