2e9w: Difference between revisions

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{{Seed}}
[[Image:2e9w.png|left|200px]]
[[Image:2e9w.png|left|200px]]


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{{STRUCTURE_2e9w|  PDB=2e9w  |  SCENE=  }}  
{{STRUCTURE_2e9w|  PDB=2e9w  |  SCENE=  }}  


===Crystal structure of the extracellular domain of Kit in complex with stem cell factor (SCF)===
===Crystal structure of the extracellular domain of Kit in complex with stem cell factor (SCF)===


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{{ABSTRACT_PUBMED_17662946}}
{{ABSTRACT_PUBMED_17662946}}


==Disease==
==About this Structure==
Known disease associated with this structure: Gastrointestinal stromal tumor, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164920 164920]], Germ cell tumors OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164920 164920]], Leukemia, acute myeloid OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164920 164920]], Mast cell leukemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164920 164920]], Mastocytosis with associated hematologic disorder OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164920 164920]], Piebaldism OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164920 164920]], Skin/hair/eye pigmentation 7, blond/brown hair OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=184745 184745]]
[[2e9w]] is a 4 chain structure of [[Proto-oncogene tyrosine-protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E9W OCA].  


==About this Structure==
==See Also==
2E9W is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E9W OCA].
*[[Proto-oncogene tyrosine-protein kinase|Proto-oncogene tyrosine-protein kinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:17662946</ref><references group="xtra"/>
<ref group="xtra">PMID:017662946</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
Line 39: Line 27:
[[Category: Growth factor cytokine]]
[[Category: Growth factor cytokine]]
[[Category: Receptor tyrosine kinase]]
[[Category: Receptor tyrosine kinase]]
[[Category: Transferase/hormone complex]]
[[Category: Transferase-hormone complex]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 08:32:18 2009''

Revision as of 11:38, 26 July 2012

File:2e9w.png

Template:STRUCTURE 2e9w

Crystal structure of the extracellular domain of Kit in complex with stem cell factor (SCF)

Template:ABSTRACT PUBMED 17662946

About this Structure

2e9w is a 4 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Yuzawa S, Opatowsky Y, Zhang Z, Mandiyan V, Lax I, Schlessinger J. Structural basis for activation of the receptor tyrosine kinase KIT by stem cell factor. Cell. 2007 Jul 27;130(2):323-34. PMID:17662946 doi:https://dx.doi.org/10.1016/j.cell.2007.05.055

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