2px6: Difference between revisions

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{{Seed}}
[[Image:2px6.png|left|200px]]
[[Image:2px6.png|left|200px]]


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{{STRUCTURE_2px6|  PDB=2px6  |  SCENE=  }}  
{{STRUCTURE_2px6|  PDB=2px6  |  SCENE=  }}  


===Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat===
===Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat===


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{{ABSTRACT_PUBMED_17618296}}
{{ABSTRACT_PUBMED_17618296}}
==Disease==
Known disease associated with this structure: Autoimmune lymphoproliferative syndrome, type IA OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=134637 134637]], Squamous cell carcinoma, burn scar-related, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=134637 134637]], Autoimmune lymphoproliferative syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=134637 134637]]


==About this Structure==
==About this Structure==
2PX6 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PX6 OCA].  
[[2px6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PX6 OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:17618296</ref><references group="xtra"/>
<ref group="xtra">PMID:017618296</ref><references group="xtra"/>
[[Category: Fatty-acid synthase]]
[[Category: Fatty-acid synthase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Tetrahydrolipstatin]]
[[Category: Tetrahydrolipstatin]]
[[Category: Thioesaterse domain]]
[[Category: Thioesaterse domain]]
 
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 08:41:30 2009''

Revision as of 21:59, 7 January 2013

File:2px6.png

Template:STRUCTURE 2px6

Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat

Template:ABSTRACT PUBMED 17618296

About this Structure

2px6 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Pemble CW 4th, Johnson LC, Kridel SJ, Lowther WT. Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat. Nat Struct Mol Biol. 2007 Aug;14(8):704-9. Epub 2007 Jul 8. PMID:17618296 doi:10.1038/nsmb1265

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