1i10: Difference between revisions

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{{Seed}}
[[Image:1i10.png|left|200px]]
[[Image:1i10.png|left|200px]]


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===HUMAN MUSCLE L-LACTATE DEHYDROGENASE M CHAIN, TERNARY COMPLEX WITH NADH AND OXAMATE===
===HUMAN MUSCLE L-LACTATE DEHYDROGENASE M CHAIN, TERNARY COMPLEX WITH NADH AND OXAMATE===


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{{ABSTRACT_PUBMED_11276087}}
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==Disease==
==About this Structure==
Known disease associated with this structure: Exertional myoglobinuria due to deficiency of LDH-A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=150000 150000]]
[[1i10]] is a 8 chain structure of [[Flavodoxin]] and [[Lactate Dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I10 OCA].


==About this Structure==
==See Also==
1I10 is a 8 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I10 OCA].
*[[Flavodoxin|Flavodoxin]]
*[[Lactate Dehydrogenase|Lactate Dehydrogenase]]


==Reference==
==Reference==
<ref group="xtra">PMID:11276087</ref><references group="xtra"/>
<ref group="xtra">PMID:011276087</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: L-lactate dehydrogenase]]
[[Category: L-lactate dehydrogenase]]
Line 35: Line 24:
[[Category: Winter, V J.]]
[[Category: Winter, V J.]]
[[Category: Dehydrogenase]]
[[Category: Dehydrogenase]]
[[Category: Oxidoreductase]]
[[Category: Rossman fold]]
[[Category: Rossman fold]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 09:19:04 2009''

Revision as of 12:39, 26 July 2012


Drag the structure with the mouse to rotate
1i10, resolution 2.30Å (default scene)
Ligands: ACT, NAI, OXM
Gene: LDHA (Homo sapiens)
Activity: L-lactate dehydrogenase, with EC number 1.1.1.27
Related: 1i0z, 9ldt, 5ldh, 1ldg
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



HUMAN MUSCLE L-LACTATE DEHYDROGENASE M CHAIN, TERNARY COMPLEX WITH NADH AND OXAMATE

Template:ABSTRACT PUBMED 11276087

About this Structure

1i10 is a 8 chain structure of Flavodoxin and Lactate Dehydrogenase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Read JA, Winter VJ, Eszes CM, Sessions RB, Brady RL. Structural basis for altered activity of M- and H-isozyme forms of human lactate dehydrogenase. Proteins. 2001 May 1;43(2):175-85. PMID:11276087

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