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{{Seed}}
[[Image:1you.png|left|200px]]
[[Image:1you.png|left|200px]]


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===Crystal structure of the catalytic domain of MMP-13 complexed with a potent pyrimidinetrione inhibitor===
===Crystal structure of the catalytic domain of MMP-13 complexed with a potent pyrimidinetrione inhibitor===


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{{ABSTRACT_PUBMED_15780611}}
{{ABSTRACT_PUBMED_15780611}}


==About this Structure==
==About this Structure==
1YOU is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YOU OCA].  
[[1you]] is a 2 chain structure of [[Matrix metalloproteinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YOU OCA].  
 
==See Also==
*[[Matrix metalloproteinase|Matrix metalloproteinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:15780611</ref><references group="xtra"/>
<ref group="xtra">PMID:015780611</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Pandit, J.]]
[[Category: Pandit, J.]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Metalloprotease]]
[[Category: Metalloprotease]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 10:36:23 2009''

Revision as of 14:24, 26 July 2012

File:1you.png

Template:STRUCTURE 1you

Crystal structure of the catalytic domain of MMP-13 complexed with a potent pyrimidinetrione inhibitor

Template:ABSTRACT PUBMED 15780611

About this Structure

1you is a 2 chain structure of Matrix metalloproteinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Blagg JA, Noe MC, Wolf-Gouveia LA, Reiter LA, Laird ER, Chang SP, Danley DE, Downs JT, Elliott NC, Eskra JD, Griffiths RJ, Hardink JR, Haugeto AI, Jones CS, Liras JL, Lopresti-Morrow LL, Mitchell PG, Pandit J, Robinson RP, Subramanyam C, Vaughn-Bowser ML, Yocum SA. Potent pyrimidinetrione-based inhibitors of MMP-13 with enhanced selectivity over MMP-14. Bioorg Med Chem Lett. 2005 Apr 1;15(7):1807-10. PMID:15780611 doi:10.1016/j.bmcl.2005.02.038

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