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| [[Image:1kzy.png|left|200px]] | | [[Image:1kzy.png|left|200px]] |
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| {{STRUCTURE_1kzy| PDB=1kzy | SCENE= }} | | {{STRUCTURE_1kzy| PDB=1kzy | SCENE= }} |
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| ===Crystal Structure of the 53bp1 BRCT Region Complexed to Tumor Suppressor P53=== | | ===Crystal Structure of the 53bp1 BRCT Region Complexed to Tumor Suppressor P53=== |
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| {{ABSTRACT_PUBMED_11877378}} | | {{ABSTRACT_PUBMED_11877378}} |
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| ==Disease== | | ==About this Structure== |
| Known disease associated with this structure: Adrenal cortical carcinoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Breast cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Choroid plexus papilloma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Colorectal cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Hepatocellular carcinoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Li-Fraumeni syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Li-Fraumeni-like syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Nasopharyngeal carcinoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Osteosarcoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]], Pancreatic cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191170 191170]]
| | [[1kzy]] is a 4 chain structure of [[P53]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KZY OCA]. |
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| ==About this Structure== | | ==See Also== |
| 1KZY is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KZY OCA].
| | *[[P53|P53]] |
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| ==Reference== | | ==Reference== |
| <ref group="xtra">PMID:11877378</ref><references group="xtra"/> | | <ref group="xtra">PMID:011877378</ref><references group="xtra"/> |
| [[Category: Homo sapiens]] | | [[Category: Homo sapiens]] |
| [[Category: Cantor, S B.]] | | [[Category: Cantor, S B.]] |
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| [[Category: Livingston, D M.]] | | [[Category: Livingston, D M.]] |
| [[Category: Pavletich, N P.]] | | [[Category: Pavletich, N P.]] |
| | [[Category: Dna binding protein]] |
| [[Category: Parallel beta sheet]] | | [[Category: Parallel beta sheet]] |
| | [[Category: Protein binding]] |
| [[Category: Tandem-brct and linker complexed with non-brct protein]] | | [[Category: Tandem-brct and linker complexed with non-brct protein]] |
| [[Category: Three-helix bundle]] | | [[Category: Three-helix bundle]] |
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| ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 10:41:25 2009''
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