1nc6: Difference between revisions
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[[Image:1nc6.png|left|200px]] | [[Image:1nc6.png|left|200px]] | ||
{{STRUCTURE_1nc6| PDB=1nc6 | SCENE= }} | {{STRUCTURE_1nc6| PDB=1nc6 | SCENE= }} | ||
===Potent, small molecule inhibitors of human mast cell tryptase. Anti-asthmatic action of a dipeptide-based transition state analogue containing benzothiazole ketone=== | ===Potent, small molecule inhibitors of human mast cell tryptase. Anti-asthmatic action of a dipeptide-based transition state analogue containing benzothiazole ketone=== | ||
{{ABSTRACT_PUBMED_12930148}} | {{ABSTRACT_PUBMED_12930148}} | ||
==About this Structure== | ==About this Structure== | ||
[[1nc6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NC6 OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:012930148</ref><references group="xtra"/> | ||
[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
[[Category: Trypsin]] | [[Category: Trypsin]] | ||
[[Category: Abraham, W M.]] | [[Category: Abraham, W M.]] | ||
[[Category: Almond, H R.]] | |||
[[Category: Andrade-Gordon, P.]] | [[Category: Andrade-Gordon, P.]] | ||
[[Category: Chattopadhyay, D.]] | [[Category: Chattopadhyay, D.]] | ||
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[[Category: Costanzo, M J.]] | [[Category: Costanzo, M J.]] | ||
[[Category: Garavilla, L de.]] | [[Category: Garavilla, L de.]] | ||
[[Category: Kauffman, J A.]] | [[Category: Kauffman, J A.]] | ||
[[Category: Maryanoff, B E.]] | [[Category: Maryanoff, B E.]] | ||
[[Category: Recacha, R.]] | [[Category: Recacha, R.]] | ||
[[Category: Yabut, S C.]] | [[Category: Yabut, S C.]] | ||
[[Category: Hydrolase]] | |||
[[Category: Protein-inhibitor complex]] | [[Category: Protein-inhibitor complex]] | ||
Revision as of 20:29, 5 December 2012
Potent, small molecule inhibitors of human mast cell tryptase. Anti-asthmatic action of a dipeptide-based transition state analogue containing benzothiazole ketone
Template:ABSTRACT PUBMED 12930148
About this Structure
1nc6 is a 1 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.
Reference
- Costanzo MJ, Yabut SC, Almond HR Jr, Andrade-Gordon P, Corcoran TW, De Garavilla L, Kauffman JA, Abraham WM, Recacha R, Chattopadhyay D, Maryanoff BE. Potent, small-molecule inhibitors of human mast cell tryptase. Antiasthmatic action of a dipeptide-based transition-state analogue containing a benzothiazole ketone. J Med Chem. 2003 Aug 28;46(18):3865-76. PMID:12930148 doi:https://dx.doi.org/10.1021/jm030050p