2uzt: Difference between revisions

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{{Seed}}
[[Image:2uzt.png|left|200px]]
[[Image:2uzt.png|left|200px]]


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{{STRUCTURE_2uzt|  PDB=2uzt  |  SCENE=  }}  
{{STRUCTURE_2uzt|  PDB=2uzt  |  SCENE=  }}  


===PKA STRUCTURES OF AKT, INDAZOLE-PYRIDINE INHIBITORS===
===PKA STRUCTURES OF AKT, INDAZOLE-PYRIDINE INHIBITORS===


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{{ABSTRACT_PUBMED_17523610}}
{{ABSTRACT_PUBMED_17523610}}


==About this Structure==
==About this Structure==
2UZT is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UZT OCA].  
[[2uzt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UZT OCA].  
 
==See Also==
*[[CAMP-dependent protein kinase|CAMP-dependent protein kinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:17523610</ref><references group="xtra"/>
<ref group="xtra">PMID:017523610</ref><references group="xtra"/>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: CAMP-dependent protein kinase]]
[[Category: CAMP-dependent protein kinase]]
Line 51: Line 42:
[[Category: Zhu, G D.]]
[[Category: Zhu, G D.]]
[[Category: Akt inhibitor]]
[[Category: Akt inhibitor]]
[[Category: Atp-binding]]
[[Category: Atp- binding]]
[[Category: Camp]]
[[Category: Camp]]
[[Category: Kinase]]
[[Category: Kinase]]
Line 63: Line 54:
[[Category: Serine/threonine-protein kinase]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Transferase]]
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:07:31 2009''

Revision as of 20:21, 7 January 2013

File:2uzt.png

Template:STRUCTURE 2uzt

PKA STRUCTURES OF AKT, INDAZOLE-PYRIDINE INHIBITORS

Template:ABSTRACT PUBMED 17523610

About this Structure

2uzt is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

See Also

Reference

  1. Zhu GD, Gandhi VB, Gong J, Thomas S, Woods KW, Song X, Li T, Diebold RB, Luo Y, Liu X, Guan R, Klinghofer V, Johnson EF, Bouska J, Olson A, Marsh KC, Stoll VS, Mamo M, Polakowski J, Campbell TJ, Martin RL, Gintant GA, Penning TD, Li Q, Rosenberg SH, Giranda VL. Syntheses of potent, selective, and orally bioavailable indazole-pyridine series of protein kinase b/akt inhibitors with reduced hypotension. J Med Chem. 2007 Jun 28;50(13):2990-3003. Epub 2007 May 25. PMID:17523610 doi:10.1021/jm0701019

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