2p3t: Difference between revisions

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{{Seed}}
[[Image:2p3t.png|left|200px]]
[[Image:2p3t.png|left|200px]]


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{{STRUCTURE_2p3t|  PDB=2p3t  |  SCENE=  }}  
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===Crystal structure of human factor XA complexed with 3-Chloro-4-(2-methylamino-imidazol-1-ylmethyl)-thiophene-2-carboxylic acid [4-chloro-2-(5-chloro-pyridin-2-ylcarbamoyl)-6-methoxy-phenyl]-amide===
===Crystal structure of human factor XA complexed with 3-Chloro-4-(2-methylamino-imidazol-1-ylmethyl)-thiophene-2-carboxylic acid [4-chloro-2-(5-chloro-pyridin-2-ylcarbamoyl)-6-methoxy-phenyl]-amide===


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{{ABSTRACT_PUBMED_17536795}}
{{ABSTRACT_PUBMED_17536795}}


==About this Structure==
==About this Structure==
2P3T is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P3T OCA].  
[[2p3t]] is a 2 chain structure of [[Factor Xa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P3T OCA].  
 
==See Also==
*[[Factor Xa|Factor Xa]]


==Reference==
==Reference==
<ref group="xtra">PMID:17536795</ref><references group="xtra"/>
<ref group="xtra">PMID:017536795</ref><references group="xtra"/>
[[Category: Coagulation factor Xa]]
[[Category: Coagulation factor Xa]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Protease]]
[[Category: Protease]]
[[Category: Protein inhibitor complex]]
[[Category: Protein inhibitor complex]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:34:54 2009''

Revision as of 17:09, 26 July 2012

File:2p3t.png

Template:STRUCTURE 2p3t

Crystal structure of human factor XA complexed with 3-Chloro-4-(2-methylamino-imidazol-1-ylmethyl)-thiophene-2-carboxylic acid [4-chloro-2-(5-chloro-pyridin-2-ylcarbamoyl)-6-methoxy-phenyl]-amide

Template:ABSTRACT PUBMED 17536795

About this Structure

2p3t is a 2 chain structure of Factor Xa with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Ye B, Arnaiz DO, Chou YL, Griedel BD, Karanjawala R, Lee W, Morrissey MM, Sacchi KL, Sakata ST, Shaw KJ, Wu SC, Zhao Z, Adler M, Cheeseman S, Dole WP, Ewing J, Fitch R, Lentz D, Liang A, Light D, Morser J, Post J, Rumennik G, Subramanyam B, Sullivan ME, Vergona R, Walters J, Wang YX, White KA, Whitlow M, Kochanny MJ. Thiophene-anthranilamides as highly potent and orally available factor xa inhibitors(1). J Med Chem. 2007 Jun 28;50(13):2967-80. Epub 2007 May 31. PMID:17536795 doi:10.1021/jm070125f

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