2ohs: Difference between revisions

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{{Seed}}
[[Image:2ohs.png|left|200px]]
[[Image:2ohs.png|left|200px]]


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{{STRUCTURE_2ohs|  PDB=2ohs  |  SCENE=  }}  
{{STRUCTURE_2ohs|  PDB=2ohs  |  SCENE=  }}  


===X-ray crystal structure of beta secretase complexed with compound 6b===
===X-ray crystal structure of beta secretase complexed with compound 6b===


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{{ABSTRACT_PUBMED_17315857}}
{{ABSTRACT_PUBMED_17315857}}


==About this Structure==
==About this Structure==
2OHS is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OHS OCA].  
[[2ohs]] is a 1 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OHS OCA].  
 
==See Also==
*[[Beta secretase|Beta secretase]]


==Reference==
==Reference==
<ref group="xtra">PMID:17315857</ref><references group="xtra"/>
<ref group="xtra">PMID:017315857</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
[[Category: Patel, S.]]
[[Category: Patel, S.]]
[[Category: Alternative splicing]]
[[Category: Alzheimer's disease]]
[[Category: Alzheimer's disease]]
[[Category: Aspartic protease]]
[[Category: Aspartic protease]]
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[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
[[Category: Signal]]
[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Zymogen]]
[[Category: Zymogen]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:52:54 2009''

Revision as of 17:36, 26 July 2012

File:2ohs.png

Template:STRUCTURE 2ohs

X-ray crystal structure of beta secretase complexed with compound 6b

Template:ABSTRACT PUBMED 17315857

About this Structure

2ohs is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Congreve M, Aharony D, Albert J, Callaghan O, Campbell J, Carr RA, Chessari G, Cowan S, Edwards PD, Frederickson M, McMenamin R, Murray CW, Patel S, Wallis N. Application of fragment screening by X-ray crystallography to the discovery of aminopyridines as inhibitors of beta-secretase. J Med Chem. 2007 Mar 22;50(6):1124-32. Epub 2007 Feb 22. PMID:17315857 doi:10.1021/jm061197u

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