2aze: Difference between revisions

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{{Seed}}
[[Image:2aze.png|left|200px]]
[[Image:2aze.png|left|200px]]


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{{STRUCTURE_2aze|  PDB=2aze  |  SCENE=  }}  
{{STRUCTURE_2aze|  PDB=2aze  |  SCENE=  }}  


===Structure of the Rb C-terminal domain bound to an E2F1-DP1 heterodimer===
===Structure of the Rb C-terminal domain bound to an E2F1-DP1 heterodimer===


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{{ABSTRACT_PUBMED_16360038}}
{{ABSTRACT_PUBMED_16360038}}


==Disease==
==About this Structure==
Known disease associated with this structure: Bladder cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=180200 180200]], Osteosarcoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=180200 180200]], Pinealoma with bilateral retinoblastoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=180200 180200]], Retinoblastoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=180200 180200]]
[[2aze]] is a 3 chain structure of [[Retinoblastoma protein]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AZE OCA].


==About this Structure==
==See Also==
2AZE is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AZE OCA].
*[[Retinoblastoma protein|Retinoblastoma protein]]


==Reference==
==Reference==
<ref group="xtra">PMID:16360038</ref><references group="xtra"/>
<ref group="xtra">PMID:016360038</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Gall, A L.]]
[[Category: Gall, A L.]]
Line 33: Line 21:
[[Category: Zheng, N.]]
[[Category: Zheng, N.]]
[[Category: Beta sandwich]]
[[Category: Beta sandwich]]
[[Category: Coiled coil]]
[[Category: Cell cycle]]
 
[[Category: Transcription]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 13:17:28 2009''

Revision as of 18:13, 26 July 2012

File:2aze.png

Template:STRUCTURE 2aze

Structure of the Rb C-terminal domain bound to an E2F1-DP1 heterodimer

Template:ABSTRACT PUBMED 16360038

About this Structure

2aze is a 3 chain structure of Retinoblastoma protein with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Rubin SM, Gall AL, Zheng N, Pavletich NP. Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release. Cell. 2005 Dec 16;123(6):1093-106. PMID:16360038 doi:10.1016/j.cell.2005.09.044

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